Post Doc in Immunology and Immunoengineering

ACS; Chapel Hill (NC); On-site; USD 60,000 - 80,000; Full time

Job summary

The Ainslie Lab at the University of North Carolina at Chapel Hill is seeking two postdoctoral researchers to join interdisciplinary projects at the interface of immunology and drug delivery.

We welcome engineers, chemists, biochemists, and immunologists to contribute to NIH-funded studies on biomaterials to modulate CAR-T/NKT cells and to evaluate tolerogenic pathways for putative vaccines against autoimmune diseases.

Qualifications

• PhD in a relevant field with strong hands-on research experience.
• Strong background in one or more of the listed techniques (flow cytometry, in vivo work).
• Excellent communication and publication record preferred.

Responsibilities

• Contribute to interdisciplinary projects at the interface of immunology and drug delivery.
• Perform in vitro and in vivo experiments; assist with data analysis.
• Develop and evaluate biomaterials to modulate CAR-T/NKT cell responses.
• Collaborate with NIH-funded projects and co-workers across disciplines.

Skills

Flow cytometry

Animal models

Mammalian cell culture

ELISA

Immune-cell isolation

Vaccines

Drug delivery

Immunological assays

In vivo evaluation

Education

PhD in immunology, chemistry, biochemistry or related field

Job description

The Ainslie Lab (https://ainslielab.web.unc.edu/) at the University of North Carolina at Chapel Hill has two postdoctoral researcher openings. We are seeking motivated scientists — including engineers, chemists, biochemists, and immunologists — to contribute to exciting interdisciplinary projects at the intersection of immunology and drug delivery. Projects are supported by two NIH-funded grants:
1. Development of biomaterials to modulate CAR-T/NKT cells for glioblastoma therapy and immune mechanistic evaluation of epitope spreading.
2. Evaluation of mechanistic tolerogenic pathways invoked by biomaterials for generation of an inverse vaccine to treat multiple sclerosis and other autoimmune diseases.

We investigate these applications both in vitro and in vivo. Candidates with a background in one or more of the following techniques are encouraged to apply: flow cytometry, animal models, mammalian cell culture, ELISA, immune-cell isolation and culture, vaccines, drug delivery systems, immunological assays, and in vivo evaluation of therapeutic or vaccine candidates. Experience with flow cytometry and animal studies is particularly desirable.

Application deadline: Oct. 30, 2026