Post-baccalaureate Fellowship

New England Biolabs; Ipswich (MA); On-site; USD 45,000 - 55,000; Full time

Benefits offered by this job

Mentorship

Proteomics exposure

Interdisciplinary research

Job summary

The Mass Spectrometry core lab within Process Development (PDMS) at New England Biolabs is seeking a Post-baccalaureate Fellow to develop methods for identifying protein degradation and to support core sample preparation and analysis. The role offers exposure to proteomics and analytical biochemistry in a collaborative environment.

Ideal candidates have a bachelor’s in chemistry/biology, hands-on lab experience, and strong communication skills.

Qualifications

• Bachelor's degree in chemistry, biology, or related field.
• Understanding of proteins and analytical tools.
• Hands-on laboratory experience with common techniques.
• Strong verbal and written communication, collaborative spirit.
• Multi-tasking and enthusiastic about learning new methods.

Responsibilities

• Biochemical assays including enzymatic assays, SDS-PAGE, and protein quantification.
• Sample preparation via proteolytic digests (in-gel, FASP, MAP).
• Operate ESI-MS/MS instruments (Ascend, QE) and calibrate LC systems.
• Process, interpret, and report data (PEAKS, Protein Metrics).
• Prepare buffers/standards for the PDMS lab and maintain instruments.

Skills

Protein biochemistry

Mass spectrometry

Lab techniques

Communication

Team collaboration

Education

Bachelor's degree in chemistry or biology

Tools

ESI-MS/MS (Ascend QE)

PEAKS

Protein Metrics

Job description

The Mass Spectrometry core lab within Process Development (PDMS) is seeking a Post-baccalaureate Fellow to develop a method that would replace in-gel digests as the means of identifying protein degradation. Additionally, this candidate will support core sample preparation and analysis for PDMS. This role is suited for an individual interested in expanding their analytical biochemistry skillset, while contributing to the mission of Process Development: developing manufacturing processes that deliver high quality reagents for our customers. The successful candidate will possess a familiarity with protein biochemistry and an interest in learning about the use of mass spectrometry for proteomics.

Primary Responsibilities:

• Biochemical assays including enzymatic assays, SDS-PAGE, and protein/peptide quantification
• Sample preparation via proteolytic digests (in-gel, FASP, MAP)
• Operation of ESI-MS/MS instruments (Ascend, QE)
• Processing, interpretation, and reporting of data (PEAKS, Protein Metrics)
• Composition of buffers and standards for use by the PDMS lab
• Calibration of laboratory instruments including mass spectrometers and liquid chromatography systems

Required qualifications:

• Bachelor’s degree in chemistry, biology, or related field
• General understanding of proteins (e.g. structures and functions) and the tools utilized for their analysis
• Hands‑on laboratory experience (e.g. pipetting, centrifugation)
• Excellent verbal and written communication skills
• Proven ability to work collaboratively
• Strong multi‑tasking skills
• Enthusiasm for learning new things

Professional Benefits:

• Hands-on experience with cutting‑edge Mass Spectrometry techniques in Proteomics
• Mentorship from experienced scientists and exposure to interdisciplinary research environments
• Opportunity to contribute to impactful research projects and develop valuable computational skills

Estimated salary for a Postbaccalaureate Fellow is $50,000 Benefits at NEB Base salary decisions depend on several factors, including, but not limited to, individual qualifications, job location, internal equity, and market data alignment.

Equal Opportunity Employer, including disabled/veterans New England Biolabs is committed to fostering an inclusive community. As an Equal Employment Opportunity employer, New England Biolabs considers applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, age, qualified physical or mental disability, transgender status, marital status, ethnicity, pregnancy, childbirth, or related medical conditions, or status as a disabled veteran or any other protected veteran, in all phases of the employment process and in compliance with applicable federal, state, and local laws and regulations. More in-depth details of EEO are available here. New England Biolabs is a participating employer in the Employment Verification (E-Verify) program. If you need an accommodation for any part of the employment process because of a medical condition or disability, please send an email to [e-mail] or call 978-927-5054 to let us know the nature of your request.

Employment at NEB offers a challenging and creative work environment in a state-of-the-art research and production facility, with a team of exceptional scientists and professional staff. The NEB culture emphasizes personal and professional growth through creativity, teamwork, respect and responsibility, while maintaining a casual campus-like working environment. Our diverse and talented team of scientists enjoy a collaborative research environment with much of the freedom and intellectual challenge of academia. Our unique corporate philosophy encourages dialogue and innovation. NEB’s philosophy can be distilled down to three core values: passion, humility and being genuine.