PhD Position available

StrainX Biotech; United States; Remote; USD 23,000 - 37,000; Full time

Job summary

Biopatrika is seeking a highly motivated PhD candidate to advance 3D bone marrow and spleen organoid models at RWTH Aachen. You will lead experimental work to recapitulate cellular interactions and enable high‑throughput drug screening, aiming to uncover novel therapeutic targets for myelofibrosis.

The project blends stem cell biology, bioengineering, and computational analysis, with collaboration across disciplines and access to cutting‑edge technologies.

Qualifications

• An MSc in molecular biology, biotechnology, biomedical sciences, stem cell biology, bioengineering, or a related field.
• Hands-on experience with mammalian cell culture, preferably including primary cells or stem cells.
• Experience with 3D cultures, organoids, iPSCs, or tissue engineering is highly desirable.
• Solid molecular biology skills and experience with functional cellular assays.
• Ability to independently design experiments, optimize protocols, troubleshoot, and analyze results.
• Excellent communication and collaboration skills in interdisciplinary teams.

Responsibilities

• Develop and optimize advanced 3D bone marrow and spleen organoid models.
• Establish scalable platforms for high-throughput drug screening and validation.
• Investigate disease mechanisms and explore therapeutic strategies to reverse fibrosis.
• Apply single-cell and spatial multiomics to characterize interactions and responses.
• Collaborate with experts in stem cell biology, bioengineering, computational biology, and clinical hematology.

Skills

Mammalian cell culture

Organoid models

High-throughput screening

Multiomics technologies

Experimental design

Education

MSc in molecular biology

Tools

Single-cell analysis

Imaging analytics

3D culture techniques

Job description

We are hiring! PhD Position available! Are you passionate about stem cell biology, organoids, and developing innovative experimental models to discover new treatments? We are looking for a highly motivated, creative, and experimentally skilled PhD candidate to join our interdisciplinary research team at Uniklinik RWTH Aachen! Building on our recent discoveries, we aim to develop the next generation of bone marrow and spleen organoid models to better understand myelofibrosis and identify novel therapeutic targets.

What will you work on?

• Develop and optimize advanced 3D bone marrow and spleen organoid models, recapitulating complex cellular interactions.
• Establish scalable platforms for high-throughput drug screening and functional target validation.
• Investigate disease mechanisms and explore novel therapeutic strategies to reverse fibrosis.
• Apply single-cell and spatial multiomics technologies to characterize cellular interactions and treatment responses.
• Collaborate closely with experts in stem cell biology, bioengineering, computational biology, and clinical hematology.

Who are we looking for?

• An MSc in molecular biology, biotechnology, biomedical sciences, stem cell biology, bioengineering, or a related field.
• Strong hands‑on experience in mammalian cell culture, ideally including primary cells, stem cells, or complex co‑culture systems.
• Experience with 3D cultures, organoids, iPSCs, or tissue engineering is highly desirable.
• Solid molecular biology skills and experience with functional cellular assays.
• The ability to independently design experiments, optimise protocols, troubleshoot, and critically analyse results.
• Excellent communication skills, a collaborative mindset, and enthusiasm for interdisciplinary research.
• Experience with high‑throughput screening, automated imaging, bioengineering, or multiomics technologies is a strong plus!
• Above all, we value scientific curiosity, creativity, technical excellence, and a proactive, hands‑on approach to research.

What do we offer?

An exciting translational research project, access to cutting‑edge technologies and patient‑derived models, and the opportunity to work in an international, highly collaborative team connecting fundamental discoveries with therapeutic development.

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