Postdoctoral Position: Tissue Engineering & 3D hPSC-Derived Models

Office of Intramural Training & Education; Bethesda (MD); On-site; USD 52,000 - 78,000; Full time

Job summary

Office of Intramural Training & Education at NIH NCATS SCTL in Bethesda seeks a postdoctoral fellow to develop 3D hiPSC-derived models and NAMs for translational research. Candidates should have a strong publication record in stem cell or related fields and experience in 3D culture, organoids, and tissue engineering.

The role offers an opportunity to work at the interface of stem cell biology, developmental biology, and translational science with access to state-of-the-art technology in a

Qualifications

• Strong publication record in stem cell biology or related field.
• Experience developing 3D hiPSC-derived models and NAMs.
• Experience with hPSC culture and directed differentiation.
• Familiarity with organoid generation and tissue engineering approaches.
• Excellent written and oral communication; ability to publish high-quality research.

Responsibilities

• Develop, optimize, and apply scalable 3D hiPSC-derived models.
• Integrate stem cell differentiation with tissue engineering to create disease models.
• Collaborate across disciplines in a multidisciplinary research environment.

Skills

Stem cell biology

Developmental biology

Organoid biology

Tissue engineering

Biomaterials

Bioengineering

3D cell culture

Microphysiological systems

Microfluidics

Quantitative tissue characterization

Education

PhD in stem cell biology or related field

Job description

Organization

NIH NCATS SCTL, Bethesda, MD and surrounding area

Scientific focus area

Biomedical Engineering and Biophysics,Stem Cell Biology

The Stem Cell Translation Laboratory at NCATS is seeking a highly motivated postdoctoral fellow to develop and engineer innovative three-dimensional (3D) human pluripotent stem cell (hPSC)-derived models and New Approach Methodologies (NAMs) to advance translational research.

About the position

We are looking for candidates with a strong research background and demonstrated publication record in stem cell biology, developmental biology, organoid biology, tissue engineering, bioengineering, biomaterials, or a closely related field. The ideal candidate will have experience developing, optimizing, and characterizing hPSC-derived 3D cell and tissue models. Relevant expertise includes hPSC culture and directed differentiation, 3D cell culture, organoid generation, biomaterials and hydrogels, microphysiological systems, microfluidics, and quantitative characterization of engineered tissues. Prior experience developing intestinal, kidney, cortical, sensory, or other hPSC-derived organoid models is particularly desirable.

The successful candidate will develop, optimize, and apply scalable 3D hPSC-derived models, integrating stem cell differentiation and developmental biology with tissue engineering approaches to generate physiologically relevant human experimental systems for disease modeling, drug discovery, and therapeutic development.

Applicants should demonstrate scientific rigor, creativity, independence, and the ability to work effectively in a collaborative, multidisciplinary research environment. Strong written and oral communication skills and a commitment to publishing high-quality research are expected. This position offers an opportunity to work at the interface of stem cell biology, developmental biology, tissue engineering, and translational science, with access to state-of-the-art technologies and NCATS’ highly collaborative research environment. We are particularly interested in candidates excited about developing next-generation, scalable human-relevant hiPSC models and NAMs.

• Cover letter describing research experience, scientific interests, and fit for the position
• Names and contact information for three professional references