Senior Lead, Cellular Biology & Hematology Discovery

Trimaren Human Capital Partners, LLC; Northern (KY); Hybrid; USD 200,000 - 290,000; Full time

Job summary

Confidential Biotech in Massachusetts seeks a leader for the Cellular Biology function who combines deep bone marrow biology with hands-on experimental work. You will drive translational models of hematologic diseases, map kinase-driven signaling, and apply scRNA-seq, ATAC-seq, and CUT&RUN to understand mechanism of action.

The role blends scientific leadership with bench work, mentoring, and cross-functional collaboration to shape candidate selection and IND-enabling activities as programs

Qualifications

• PhD with extensive pharmacology/biology experience in hematology.
• Expertise in bone marrow biology and drug discovery applications.
• Hands-on development of cell-based models for hematologic diseases.
• Strong background in kinase signaling and intracellular pathways.
• Experience with functional genomic and epigenomic tools (scRNA-seq, ATAC-seq, CUT&RUN).
• Ability to design rigorous genomic experiments and interpret results.

Responsibilities

• Lead the Cellular Biology function and set scientific strategy.
• Develop translational cellular models of hematologic diseases, especially bone marrow.
• Characterize pharmacodynamic properties of novel therapeutics.
• Identify druggable targets and contribute to go/no-go decisions.
• Integrate multi-omics data to generate mechanistic hypotheses.
• Mentor scientists and build modern cellular biology capabilities.
• Collaborate across R&D and manage CROs and external partners.

Skills

Bone marrow biology

Hematology

Cell biology

Kinase signaling

Translational models

Single-cell genomics

Education

PhD in relevant field

MS with 10+ years experience

Tools

Flow cytometry

PCR

ELISA

Cell culture

ATAC-seq

scRNA-seq

CUT&RUN

Job description

Confidential Biotech in Massachusetts seeks a leader for the Cellular Biology function who combines deep bone marrow biology with hands-on experimental work. You will drive translational models of hematologic diseases, map kinase-driven signaling, and apply scRNA-seq, ATAC-seq, and CUT&RUN to understand mechanism of action.

The role blends scientific leadership with bench work, mentoring, and cross-functional collaboration to shape candidate selection and IND-enabling activities as programs