Overnight Lead, cGMP Manufacturing Ops

Vertex Pharmaceuticals; Boston (MA); On-site; USD 88,000 - 147,000; Full time

Job summary

Vertex Pharmaceuticals is seeking a Supervisor, Manufacturing Operations to lead first/second/overnight shift manufacturing with a focus on cGMP compliance and efficient execution. You will assign work according to schedules, oversee equipment setup, operation, and cleaning, and ensure accurate batch record documentation.

The role requires a Bachelor’s degree in a scientific/engineering field and 6+ years of related experience, including prior supervision and aseptic manufacturing exposure.

Qualifications

• Bachelor's degree in a scientific, technical or engineering discipline.
• 6+ years of experience or the equivalent combination of education and experience.
• Prior supervisory or leadership experience preferred.
• Prior cell therapy and aseptic manufacturing experience preferred.
• Prior POMS MES experience preferred.

Responsibilities

• Lead and supervise daily manufacturing operations.
• Assign work to shift personnel based on production schedules and plans.
• Oversee cGMP manufacturing activities including equipment setup, operation, disassembly, and cleaning.
• Execute and witness batch record instructions during cGMP operations to ensure compliant documentation.
• Perform real-time on-the-floor batch record review.
• Interface with cross-functional teams to support facility operations and maintenance.

Skills

Leadership

Team supervision

cGMP knowledge

SOP adherence

Communication

Problem solving

Education

Bachelor's degree in science/engineering

Tools

POMS MES

Job description

Vertex Pharmaceuticals is seeking a Supervisor, Manufacturing Operations to lead first/second/overnight shift manufacturing with a focus on cGMP compliance and efficient execution. You will assign work according to schedules, oversee equipment setup, operation, and cleaning, and ensure accurate batch record documentation.

The role requires a Bachelor’s degree in a scientific/engineering field and 6+ years of related experience, including prior supervision and aseptic manufacturing exposure.