Operations and Analytics Associate Director

Vertex Pharmaceuticals LLC; Boston, Northern (MA, KY); Hybrid; USD 168,000 - 252,000; Full time

Job summary

Vertex Pharmaceuticals LLC is seeking an Operations and Analytics Associate Director to lead sophisticated analyses, build financial models, and deliver insights that inform market access strategy and planning in a hybrid work environment.

The role involves partnering with cross-functional teams to forecast net revenue, integrate brand learnings, and present findings to senior leadership, shaping decisions across current and potential indications.

Qualifications

• Bachelor's degree in quantitative discipline required; MBA or equivalent preferred.
• 8 years of progressive experience in market access, forecasting, or finance, with pharma/biopharma exposure.

Responsibilities

• Lead analyses and build financial models to address market access questions.
• Forecast net revenue projections with the GTN team and inform year plans.
• Respond to ad-hoc analytical requests and deliver timely insights.

Skills

Forecasting

Data analysis

Power BI

SQL

Excel modeling

Presentation

Education

Bachelor's degree in quantitative field

MBA or equivalent

Tools

Oracle

Hyperion

SAP

Job description

Job Description General Summary

The Operations and Analytics Associate Director leads sophisticated analyses, develops financial models, and generates insights to address strategic market access questions, presenting findings effectively and succinctly to leadership. The role requires the extraction and synthesis of relevant data to deliver timely insights into the underlying factors driving forecasts and variances to plan, while delivering forward-looking perspectives that inform and drive key business decisions— supporting both approved and potential future indications

Key Duties and Responsibilities

• Work independently to surface insights from internal data sets and secondary sources that answer key business questions and inform access and commercial decisions
• Play a key role in the forecasting process, partnering with the GTN team to integrate net revenue projections, assumptions, and brand learnings to ensure accuracy & timeliness for current and future year planning
• Manage and respond to ad‑hoc analytical requests from business partners, delivering timely and accurate insights that support decision‑making
• Develop and manage a GPO performance measurement process, including monthly reporting, dashboard development, and analytical insights that evaluate contracting effectiveness and guide business decisions
• Partner cross‑functionally across Account Teams, Strategy, Finance, HEOR, Government Pricing, and Trade to align on assumptions, integrate diverse inputs, and ensure analytical deliverables reflect current business priorities
• Lead the development of presentations for senior and executive management that synthesize trends, forecasts and the potential financial impact of new and pending state and federal policies, pricing scenarios and payer mix
• Work as needed to “in‑source” vendor tools and responsibilities into the team scope while maintaining business continuity

Knowledge and Skills

• Excellent working knowledge of the evolving access, pricing, and reimbursement dynamics and health system environment in the US Prior experience in developing short and long‑term commercial forecasts, GTN models, and pricing and contracting break‑even analysis Experience in dashboard development such as Power BI or Tableau a plus Track record of producing insights and analysis across payer channel (e.g., Commercial, Medicare, Medicaid, etc.) and communicating impacts and sensitivity analysis to senior management Demonstrated understanding of contracting with PBMs, trade and distribution partners, and strategies for value‑driven pricing and reimbursement Working knowledge and familiarity with syndicated Market Access databases (IQVIA, MMIT, etc.) Exposure and understanding of financial systems (such as Oracle, Hyperion, SAP, etc.) Advanced proficiency in complex Excel modeling and PowerPoint presentations Proficient in analyzing large data sets such as prescription and claims data using a statistical analysis language (e.g., SQL) Knowledge of additional scripting languages such as Python is a plus, as well as working knowledge of AI analytical tools Strong analytical and business acumen: intellectual curiosity, motivation, and ability to structure problems, diagnose issues, and triangulate with multiple approaches while keeping sight of the big picture Excellent communication and presentation skills to influence and collaborate with a diverse stakeholder community to achieve actionable and timely results through establishing strong and sustainable relationships Ability to work independently in a complex, ambiguous, and highly matrixed environment

Education and Experience

Bachelor’s degree in a quantitative discipline required (e.g., Engineering, Statistics, Economics, Finance); advanced degree (MBA or equivalent) preferred 8 years of progressive experience in market access, forecasting, or finance, with significant exposure to pharma/biopharma financial and managed markets data sources, or the equivalent combination of education and experience

Pay Range: $168,000 - $252,000

Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week‑long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation: Hybrid-Eligible Or On‑Site Eligible

Flex Eligibility Status: In this Hybrid‑Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On‑Site: work five days per week on‑site with ad‑hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI‑Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]

Help Us Achieve Our Mission

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life‑shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion‑dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1‑mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha‑1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.