Executive Director, Commercial Analytics

Vertex Pharmaceuticals Inc (US); Boston (MA); Hybrid; USD 266,000 - 398,000; Full time

Job summary

Vertex Pharmaceuticals seeks an Executive Director, Commercial Analytics to lead the Commercial Analytics COE within US Commercial, overseeing forecasting, performance analytics, and market research across NA, Global, and Early Pipeline. This senior role partners with Commercial leadership to elevate analytics as a core capability for decision-making and launch excellence.

The role requires advanced quantitative expertise, broad leadership, and a track record of delivering strategic insights

Qualifications

• Advanced degree in a quantitative, scientific, or business discipline.
• Deep experience in commercial forecasting, analytics, and market research in biotech/pharma or similar industries.
• Proven success leading large, multi-disciplinary analytics organizations and influencing executive leaders.

Responsibilities

• Lead the Commercial Analytics COE, overseeing 20-25 FTEs organized by disease area verticals.
• Define enterprise analytics vision, operating model, governance, and prioritization to maximize business impact.
• Provide executive oversight of short- and mid-range forecasting and participation in Long Range Planning.
• Enable scenario planning and revenue impact analysis in partnership with Finance, Supply Chain, and Commercial Strategy.
• Own national and sub-national analytics, KPI frameworks, and variance analysis versus forecast.
• Lead all North America market research and all Global and Early Pipeline market research.

Skills

Executive leadership

Strategic analytics

Forecasting

Market research

Education

Advanced degree in quantitative/scientific/business

Job description

Job Description General Summary

The Executive Director, Commercial Analytics leads the Commercial Analytics Center of Excellence within US Commercial, providing enterprise-level oversight across forecasting, performance and strategic analytics, sub-national and field analytics, omnichannel and media analytics, and market research across North America, Global, and Early Pipeline. This role is a senior strategic partner to Commercial leadership and is accountable for elevating analytics from a tactical service into a core commercial capability that enables executive decision-making, launch excellence, and optimized investment.

Key Duties and Responsibilities

Lead the Commercial Analytics (CA) COE, overseeing ~20-25 FTEs organized by disease area (DA) verticals. Define enterprise analytics vision, operating model, governance, and prioritization to maximize business impact. Establish analytics and forecasting excellence, including best practices, vendor strategy, and innovation. Provide executive oversight of short- and mid-range (LE) forecasting and participation in Long Range Planning (LRP). Enable scenario planning and revenue impact analysis in partnership with Finance, Supply Chain, and Commercial Strategy. Own national and sub-national analytics, KPI frameworks, and variance analysis versus forecast. Support go-to-market decision-making including field force sizing, market evaluation, and launch readiness. Lead all North America market research and all Global and Early Pipeline market research for inline and pipeline disease areas. Establish marketing science excellence, including best practices, vendor strategy, and innovation. Oversee omnichannel, media, and field analytics to optimize marketing mix, targeting, and customer engagement. Enable field leadership through actionable insights, reporting, and performance metrics. Lead senior DA Leaders as single points of accountability, embedded within BULTs. Balance people leadership with hands‑on strategic analytics and decision support. Serve as a trusted advisor to EC-level stakeholders and cross‑functional partners across Commercial, Medical, HEOR, Market Access, Finance, and Supply Chain. Build and scale a high‑performing analytics organization, including Senior Director–level leaders. Manage a growing operating budget (>$10M growth) with a focus on efficiency and impact.

Knowledge and Skills

Enterprise, strategic mindset with strong executive presence. Ability to lead through complexity and organizational change. Values-driven leader focused on accountability and continuous improvement.

Education and Experience

Advanced degree in a quantitative, scientific, or business discipline. Deep experience in commercial forecasting, analytics, and market research in biotech/pharma or similar industries. Proven success leading large, multi-disciplinary analytics organizations and influencing executive leaders. Experience supporting global and pipeline portfolios. Prior experience operating within or alongside business unit leadership teams. Exposure to advanced analytics, digital, and AI-enabled decision support.

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends.

We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision‑making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range

$265,600 - $398,400

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.

From medical, dental and vision benefits to generous paid time off (including a week‑long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status

In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Help Us Achieve Our Mission

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For.

For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them.

Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]