Onsite Senior Upstream Biotech Process Engineer

Piper Companies; Holly Springs (NC); On-site; USD 90,000 - 103,000; Full time

Benefits offered by this job

Medical

Dental

Vision

Sick leave

401K

Job summary

Piper Companies seeks a Senior Upstream Process Engineer to join a leading biotechnology organization onsite in Holly Springs, North Carolina. The role provides technical support for upstream manufacturing, partnering with cross-functional teams to improve equipment reliability, resolve production challenges, and advance process excellence in a regulated environment.

Qualifications include a bachelor's degree in a related engineering field, 6+ years of pharma/biotech process engineering

Qualifications

• Bachelor's degree in Chemical Engineering, Mechanical Engineering, Bioprocess Engineering, or a related technical discipline.
• 6+ years of process engineering experience within pharmaceutical, biotechnology, biologics, or other regulated manufacturing environments.
• Hands-on experience supporting stainless steel bioprocess equipment, including tanks, filtration systems, bioreactors, or related upstream process equipment.
• Strong troubleshooting abilities involving process controls, automation systems, temperature control, pH control, dissolved oxygen management, and manufacturing operations.
• Experience working with DeltaV or similar distributed control systems, with the ability to collaborate effectively with automation and controls teams.

Responsibilities

• Provide day-to-day engineering support for upstream manufacturing processes, ensuring production equipment operates safely, efficiently, and consistently.
• Lead troubleshooting efforts involving process equipment, control systems, and manufacturing operations, identifying root causes and driving effective resolutions.
• Manage and support quality and compliance activities, including investigations, deviations, corrective actions, and change management documentation.
• Serve as a technical resource for media preparation, bioreactor, filtration, and harvest systems while collaborating with Maintenance, Automation, and Instrumentation teams.
• Monitor critical production activities, assist with process improvements, and support operational readiness during manufacturing campaigns.

Skills

Troubleshooting

Process controls

Automation systems

Cross-functional collaboration

Education

Bachelor's degree in Chemical Engineering, Mechanical Engineering, Bioprocess Engineering, or related technical discipline

Tools

DeltaV

Job description

Piper Companies seeks a Senior Upstream Process Engineer to join a leading biotechnology organization onsite in Holly Springs, North Carolina. The role provides technical support for upstream manufacturing, partnering with cross-functional teams to improve equipment reliability, resolve production challenges, and advance process excellence in a regulated environment.

Qualifications include a bachelor's degree in a related engineering field, 6+ years of pharma/biotech process engineering