Onsite Biochemical & Cellular Pharmacology Scientist

Pharmaceutical Company; South San Francisco (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

Pharmaceutical Company in San Diego, CA seeks a Scientist to advance biochemical and cellular assay development to support early drug discovery. The role focuses on induced proximity-based assays, protein interactions, and translating findings into actionable insights.

The candidate will design and optimize assays, validate data, and collaborate across cross-functional teams in a fast-paced, onsite lab environment.

Qualifications

• Demonstrated experience designing, developing, and validating biochemical and cellular assays.
• Direct experience with induced proximity mechanisms and modalities such as molecular glues and ternary complexes.
• Strong understanding of protein-protein and protein-small molecule interactions.
• Proficiency in quantitative data analysis using GraphPad Prism, Python, or R.

Responsibilities

• Design, develop, and optimize biochemical and cell-based assays to quantify interactions.
• Develop and execute induced proximity-based assays to support early drug discovery.
• Conduct routine compound screening and validation studies for leads.
• Analyze data, troubleshoot experiments, and ensure reproducibility.
• Collaborate with Pharmacology, Protein Science, Medicinal Chemistry, and Research Biology.
• Prepare technical reports and present results in project meetings.
• Evaluate new technologies to improve assay performance.

Skills

Biochemical assays

Cell-based assays

Induced proximity

Molecular glues

Ternary complexes

Protein interactions

Data analysis

Education

Bachelor's or Master's in Biochemistry, Biophysics, Cellular Biology or Molecular Biology

Tools

GraphPad Prism

Python

R

Job description

Pharmaceutical Company in San Diego, CA seeks a Scientist to advance biochemical and cellular assay development to support early drug discovery. The role focuses on induced proximity-based assays, protein interactions, and translating findings into actionable insights.

The candidate will design and optimize assays, validate data, and collaborate across cross-functional teams in a fast-paced, onsite lab environment.