Onsite Senior Discovery Biologist: GPCR & Cell-Based Assays

Superluminal Medicines Inc.; Boston (MA); On-site; USD 150,000 - 176,000; Full time

Benefits offered by this job

401(k) match

Equity

Massachusetts transportation subsidy

Unlimited paid time off

Job summary

Superluminal Medicines is seeking a highly motivated drug discovery biologist to join the growing Discovery Biology team. The role is hands-on, wet-lab focused, leading programs from hit finding through early discovery and requiring on-site work five days a week.

The successful candidate will design and execute broad cell-based assays to interrogate GPCR signaling, generate and manage data, and collaborate with computational, chemistry, and protein science teams.

Qualifications

• Ph.D. in Biology or related life sciences with 5+ years of industry experience.
• Hands-on experience developing, executing, and interpreting cell-based assays across formats and platforms, including functional assays, target engagement assays, kinetic assays, plate-based assays, flow cytometry, and high-content imaging.
• Small molecule drug discovery experience required.
• Demonstrated problem‑solving skills and ability to develop innovative solutions to complex challenges.
• GPCR biology experience is highly desired.
• Experience with assay automation or laboratory robotics is a plus.

Responsibilities

• Hands‑on wet lab role driving programs from hit finding through early discovery.
• Design, develop and execute a broad array of cell‑based assays to interrogate GPCR function and signaling.
• Generate, analyze, document, and upload experimental and routine screening data to company databases in a timely and accurate manner.
• Collaborate cross‑functionally with computational, chemistry and protein science colleagues to conceptualize, design, and execute novel screening assays.
• Regularly communicate findings with program teams and present at project & company-wide meetings.
• Ensure compliance with established laboratory practices, SOPs, and company policies, including both wet lab and electronic data management requirements.

Skills

cell-based assays

GPCR biology

drug discovery

problem solving

Education

Ph.D. in Biology or related life sciences

Tools

Flow cytometry

High-content imaging

Plate-based assays

Kinetic assays

High-throughput screening

Laboratory automation

Job description

Superluminal Medicines is seeking a highly motivated drug discovery biologist to join the growing Discovery Biology team. The role is hands-on, wet-lab focused, leading programs from hit finding through early discovery and requiring on-site work five days a week.

The successful candidate will design and execute broad cell-based assays to interrogate GPCR signaling, generate and manage data, and collaborate with computational, chemistry, and protein science teams.