Oncology QP & Pharmacometrics Leader — Senior Director

MSD; Rahway (NJ); Hybrid; USD 210,000 - 331,000; Full time

Job summary

MSD is seeking a Senior Director, Group Leader to lead the Quantitative Pharmacology and Pharmacometrics – Oncology (QP2 Oncology) team. You will shape strategy, oversee modeling and translational PK/PD efforts, and drive regulatory and development decisions with a focus on MIDD approaches.

You will mentor a team of scientists, collaborate with Clinical Development, Translational Medicine, Biostatistics, and Regulatory, and partner with preclinical teams to translate nonclinical findings into

Qualifications

• Ph.D. in pharmacokinetics/pharmacodynamics, pharmacometrics, mathematics, statistics/biostatistics, chemical/biomedical engineering, or related discipline with ≥10 years of relevant pharmaceutical industry experience.
• Master’s, PharmD, or equivalent degree with ≥15 years of relevant pharmaceutical industry experience, with increasing responsibility and leadership.

Responsibilities

• Lead quantitative pharmacology strategy across oncology programs to inform key development decisions (dose, trial design, go/no-go).
• Develop and implement integrated MIDD strategies to support decision making across development stages.
• Collaborate with Translational, Clinical, Biostatistics, and Regulatory teams to integrate quantitative insights into strategies.
• Provide leadership and oversight to a team of QP2 scientists, ensuring high-quality deliverables.

Skills

Strategic leadership

Cross-functional collaboration

Team leadership

Regulatory strategy

Model-informed drug development

Pharmacometric modeling

Biostatistics

Translational PK/PD

Communication

Problem solving

Leadership

Stakeholder management

Project management

Education

Ph.D. in pharmacokinetics/pharmacodynamics

≥10 years pharma industry experience

Master’s, PharmD, or equivalent

≥15 years pharma industry experience

Tools

None

Job description

MSD is seeking a Senior Director, Group Leader to lead the Quantitative Pharmacology and Pharmacometrics – Oncology (QP2 Oncology) team. You will shape strategy, oversee modeling and translational PK/PD efforts, and drive regulatory and development decisions with a focus on MIDD approaches.

You will mentor a team of scientists, collaborate with Clinical Development, Translational Medicine, Biostatistics, and Regulatory, and partner with preclinical teams to translate nonclinical findings into