Oncology Clinical Trial Manager — Hybrid (Boston)

Frontier Medicines Corporation; Boston (MA); Hybrid; USD 125,000 - 170,000; Full time

Benefits offered by this job

Health Care Plan

Retirement Plan (401k)

Life Insurance

Paid Time Off

Family Leave

Short Term Disability

Long Term Disability

Training & Development

Free Food & Snacks

Wellness Resources

Stock Option Plan

Job summary

Frontier Medicines Corporation seeks two Sr. Clinical Trial Managers to oversee oncology trial execution with hands-on ownership from feasibility to close-out. In Boston, this hybrid role requires 2–3 days on-site weekly, partnering with CROs and trial sites, and coordinating cross-functional trial activities.

You will monitor timelines, budgets, and TMF quality, while ensuring regulatory compliance and inspection readiness, with frequent cross-functional interaction and travel as needed.

Qualifications

• Bachelor’s degree in a scientific, healthcare, or related field required.
• 5-7 years of Clinical Trial Manager/SCTM or Clinical Project Management experience, ideally supporting oncology trials.
• Experience with oncology studies strongly preferred.
• Vendor and CRO management experience.
• Strong working knowledge of ICH-GCP guidelines and clinical trial regulations.
• Excellent organizational, problem-solving, and time management skills with strong attention to detail.
• Strong written and verbal communication skills with a collaborative, team-oriented approach.
• Comfortable in a fast-paced, dynamic environment; proactive, hands-on mindset.
• Legally authorized to work in the United States.

Responsibilities

• Support day-to-day activities within one or more clinical trials, including feasibility assessments, site selection, start-up, maintenance, and close-out.
• Serve as a key operational point of contact for CROs and trial sites, identifying and escalating potential issues.
• Assist with oversight of CRO and vendor set-up, liaising with CROs to ensure timely study initiation.
• Review site-level regulatory documents and ensure inspection readiness and TMF quality.
• Identify operational challenges and propose mitigation plans with senior team members.
• Review protocols, informed consent forms, case report forms, and other study documents as needed.
• Monitor study performance metrics, timelines, and CRO/vendor invoices; flag discrepancies.
• Maintain timely study registration and updates on ClinicalTrials.gov and other registries.
• Coordinate Clinical Trial Team meetings and drive action item follow-up.
• Maintain trackers, databases, and document repositories; provide regular study updates.

Skills

Clinical Trial Management

Oncology Trials

Vendor Management

CRO Management

ICH-GCP Knowledge

Regulatory Compliance

Communication Skills

Education

Bachelor’s degree in a scientific/healthcare field

Job description

Frontier Medicines Corporation seeks two Sr. Clinical Trial Managers to oversee oncology trial execution with hands-on ownership from feasibility to close-out. In Boston, this hybrid role requires 2–3 days on-site weekly, partnering with CROs and trial sites, and coordinating cross-functional trial activities.

You will monitor timelines, budgets, and TMF quality, while ensuring regulatory compliance and inspection readiness, with frequent cross-functional interaction and travel as needed.