Hybrid Oncology Clinical Trial Manager

C4 Therapeutics, Inc.; Massachusetts; Hybrid; USD 139,000 - 153,000; Full time

Job summary

C4 Therapeutics is seeking an experienced Clinical Trial Manager to lead oncology trials from First in Human through Phase III. The role requires managing day-to-day operations, cross-functional collaboration, and ensuring timelines, budgets, and quality with CRO partners.

The position is hybrid, with regular work at the Watertown, MA office. Ideal candidates have a strong background in clinical operations, regulatory knowledge, and a proven ability to drive study milestones while maintaining

Qualifications

• Bachelor’s degree in health/life sciences or related field.
• Minimum five years of progressive clinical operations experience, including trial management across development phases.
• Experience coordinating CROs and third-party vendors.
• Knowledge of FDA regulations and ICH/GCP guidelines.
• Ability to lead cross-functional teams and manage study budgets.

Responsibilities

• Lead day-to-day operational aspects of clinical studies from protocol through study report.
• Collaborate with cross-functional team members on study operations strategy.
• Establish study timelines with stakeholders and CROs; report metrics.
• Develop and manage study budgets with finance; vendor invoice reviews.
• Identify, evaluate, and select CRO/third-party vendors; manage vendor relationships.
• Prepare for Safety Review Committee meetings and investigator meetings as needed.
• Contribute to study documents such as protocols, CRFs, and ICH/IND/CTAs documents.
• Ensure compliance with SOPs, ICH/GCP, and local regulations.

Skills

Trial management

Cross-functional leadership

Budget management

FDA regulations

ICH/GCP knowledge

Education

Bachelor’s degree in health/life sciences

Job description

C4 Therapeutics is seeking an experienced Clinical Trial Manager to lead oncology trials from First in Human through Phase III. The role requires managing day-to-day operations, cross-functional collaboration, and ensuring timelines, budgets, and quality with CRO partners.

The position is hybrid, with regular work at the Watertown, MA office. Ideal candidates have a strong background in clinical operations, regulatory knowledge, and a proven ability to drive study milestones while maintaining