Lead Oncology Clinical PK/PD & Pharmacometrics Scientist

Immunomeinc; Bothell (WA); On-site; USD 186,000 - 212,000; Full time

Job summary

Immunome, Inc. is seeking a Principal Scientist in Clinical Pharmacology and Pharmacometrics to lead quantitative pharmacology for oncology programs. You will guide PK/PD and PBPK analyses, inform dose selection, and work with CROs and internal teams to shape development strategy.

The role requires a Ph.D. or PharmD with 2–5 years in regulated biotech, with ADC/RLT experience preferred and strong regulatory interaction skills.

Qualifications

• Ph.D. or PharmD in a relevant scientific discipline.
• 2–5 years' experience in pharma/biotech in a regulated environment.
• Experience with noncompartmental and PBPK analyses and pharmacometric modeling.
• Proficiency with WINNONLIN, NONMEM, MONOLIX or similar software.
• Knowledge of R, R-shiny, SAS, MATLAB, NONMEM, MONOLIX, PBPK tools.
• Experience in development of anti-cancer agents, preferably ADCs or RLTs.
• Excellent written and verbal communication; collaborative mindset.

Responsibilities

• Formulate and deliver CP&MS strategy for late-stage and early assets.
• Apply PK/PD, PBPK and modeling approaches to inform dose selection.
• Coordinate with CROs and scientists to run clinical pharmacology studies.
• Drive program strategy, study design, and regulatory document preparation.

Skills

Oncology drug development

Regulatory strategy

Cross-functional leadership

Quantitative pharmacology

Communication skills

Education

Ph.D. or PharmD in a relevant scientific discipline

Tools

WINNONLIN

NONMEM

MONOLIX

R

R-shiny

SAS

MATLAB

PBPK tools

Job description

Immunome, Inc. is seeking a Principal Scientist in Clinical Pharmacology and Pharmacometrics to lead quantitative pharmacology for oncology programs. You will guide PK/PD and PBPK analyses, inform dose selection, and work with CROs and internal teams to shape development strategy.

The role requires a Ph.D. or PharmD with 2–5 years in regulated biotech, with ADC/RLT experience preferred and strong regulatory interaction skills.