Neuroscience Postdoc: TDP-43 Neurodegeneration & iPSC Models

Novartis Group Companies; Cambridge (MA); On-site; USD 87,000 - 107,300; Full time

Benefits offered by this job

Health benefits

401(k) with company match

Vacation & holidays

Job summary

Novartis Biomedical Research Postdoctoral Fellowship Program invites applications for a Discovery Postdoctoral Fellow in Cambridge, MA to investigate TDP-43-driven neurodegeneration using human iPSC-derived neuron-glia systems, proteomics, transcriptomics, and multiomics integration.

The program trains early career scientists through rigorous research, AI-enabled biomedical approaches, and leadership development, with a three-year duration and full-time commitment. Start date October 1, 2026.

Qualifications

• PhD (or equivalent) conferred in 2026 only; immediately following PhD training.
• Publications, presentations, patents, or equivalent demonstrated.
• Strong expertise in neurobiology, molecular and cell biology, or biochemistry.
• Experience with human iPSC-derived neuronal or glial models.
• Experience in confocal microscopy and high-content imaging and analysis.
• Demonstrated ability to analyze complex proteomics datasets.
• Desirable: TDP-43 biology and protein interactome mapping / chemo-proteomics.

Responsibilities

• Design and execute an independent, hypothesis-driven research program.
• Develop and apply human iPSC-based neuron and glial models.
• Utilize genomics, proteomics, and transcriptomics approaches.
• Analyze and integrate multiomics datasets.
• Collaborate with interdisciplinary teams across research units.
• Communicate findings through presentations and peer-reviewed publications.

Skills

Neurobiology

Molecular & Cell Biology

Biochemistry

iPSC-derived neurons/glia

Proteomics

Genomics

Transcriptomics

Multiomics

Confocal microscopy

High-content imaging

Data analysis

Education

PhD in neuroscience or related field

Tools

Halo Mapping

Job description

Novartis Biomedical Research Postdoctoral Fellowship Program invites applications for a Discovery Postdoctoral Fellow in Cambridge, MA to investigate TDP-43-driven neurodegeneration using human iPSC-derived neuron-glia systems, proteomics, transcriptomics, and multiomics integration.

The program trains early career scientists through rigorous research, AI-enabled biomedical approaches, and leadership development, with a three-year duration and full-time commitment. Start date October 1, 2026.