Neurodegeneration Proteomics Scientist

University of California - San Francisco; San Francisco (CA); On-site; USD 97,000 - 257,000; Full time

Job summary

University of California, San Francisco is seeking an experienced Researcher in Neuroscience to investigate molecular mechanisms of neurodegenerative diseases. You will develop proteomics workflows, lead experiments from hypothesis to validation, and work with disease-relevant cellular models including iPSC-derived neurons.

The role requires substantial neuroscience and proteomics expertise, scientific independence, and the ability to coordinate projects, mentor junior researchers, and

Qualifications

• PhD and postdoctoral experience in neuroscience, neurobiology, proteomics, or related field.
• Strong proteomics expertise applied to protein interactions and cellular pathways.
• Hands-on molecular biology, biochemistry and cell biology incl. cloning, PCR, Western blot.
• Independently design and lead complex experiments from hypothesis to results.
• Develop, optimize and implement robust experimental workflows.
• Manage multiple research projects and timelines.
• Mentor junior researchers and provide technical guidance.
• Excellent written and verbal communication for manuscripts and grants.

Responsibilities

• Develop and optimize proteomics workflows and systems.
• Lead experimental investigations from hypothesis through data interpretation.
• Work with mammalian cells and disease models, including iPSC-derived neurons.
• Collaborate with proteomics and computational experts to derive insights.
• Contribute to publications, grant applications, and research proposals.

Skills

Neuroscience

Proteomics

Molecular biology

Experimental design

Project management

Mentoring

Science communication

Education

PhD in neuroscience or related field

Tools

AP-MS

BioID

TurboID

CRISPR

iPSC neurons

Computational tools

Job description

University of California, San Francisco is seeking an experienced Researcher in Neuroscience to investigate molecular mechanisms of neurodegenerative diseases. You will develop proteomics workflows, lead experiments from hypothesis to validation, and work with disease-relevant cellular models including iPSC-derived neurons.

The role requires substantial neuroscience and proteomics expertise, scientific independence, and the ability to coordinate projects, mentor junior researchers, and