Proteomics Neuroscience Researcher

University of California, San Francisco; San Francisco (CA); On-site; USD 97,000 - 257,000; Full time

Job summary

The University of California, San Francisco is seeking an experienced Researcher to investigate molecular mechanisms of neurodegenerative diseases, focusing on Alzheimer’s disease and ALS, defining protein–protein interaction networks, and understanding cellular pathways.

The role involves leading proteomics workflows, managing projects, mentoring junior researchers, contributing to publications and grants, and communicating findings to interdisciplinary audiences.

Qualifications

• PhD and postdoctoral experience in neuroscience, neurobiology, proteomics with independence.
• Strong proteomics expertise applied to protein interactions and cellular pathways.
• Hands-on molecular biology, biochemistry, and cell biology experience.
• Ability to design and lead complex experiments from hypotheses to results.
• Experience developing workflows and reproducible research methodologies.
• Experience managing multiple projects and coordinating timelines.
• Ability to mentor junior researchers and provide technical guidance.
• Excellent written and verbal communication; contribute to manuscripts and grants.

Responsibilities

• Develop and optimize proteomics workflows and experimental systems.
• Establish robust experimental systems and validate key findings.
• Collaborate with proteomics and computational teams to derive insights.
• Lead research projects, coordinate collaborations, and mentor others.
• Contribute to publications, grant applications, and presentations.
• Communicate findings clearly to interdisciplinary audiences.

Skills

Proteomics expertise

Molecular biology

Cell biology

Hypothesis-driven research

Mentoring

Scientific communication

Education

PhD in neuroscience/proteomics

Tools

AP-MS

BioID

TurboID

CRISPR engineering

Mass spectrometry

Job description

The University of California, San Francisco is seeking an experienced Researcher to investigate molecular mechanisms of neurodegenerative diseases, focusing on Alzheimer’s disease and ALS, defining protein–protein interaction networks, and understanding cellular pathways.

The role involves leading proteomics workflows, managing projects, mentoring junior researchers, contributing to publications and grants, and communicating findings to interdisciplinary audiences.