Molecular Biology & Antibody Library Scientist

Antibody Design Labs; San Diego (CA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Competitive salary

Health insurance

Paid time off

Job summary

Antibody Design Labs in San Diego is seeking a Research Scientist specializing in Molecular Biology and Antibody Engineering to lead library construction programs, drive sequence diversity design, and manage timelines to deliver high-quality discovery services in a fast-paced CRO setting.

You will collaborate on phage/yeast display libraries, oversee QC and documentation, and contribute to experimental design and client communication.

Qualifications

• Ph.D. in Molecular Biology, Biochemistry, Biotechnology, or related life sciences with 1–3 years post-degree or industry experience; or an MS with 5+ years hands-on industry experience in antibody engineering or display technologies.
• Expertise in constructing complex molecular libraries (synthetic, semi-synthetic, or immunized) and understanding immunoglobulin gene structures, variable domain cloning, and CDR diversification strategies.
• Proficiency in advanced molecular cloning techniques, library QC metrics, and sequence analysis software.

Responsibilities

• Lead end-to-end design, construction, and characterization of antibody and peptide libraries (phage, yeast, or related platforms).
• Collaborate on sequence diversity schemes, codon optimization, humanization, and affinity maturation to build diverse libraries.
• Manage workflows and timelines for client and internal discovery programs, ensuring on-time delivery of project deliverables.
• Maintain precise project documentation, SOPs, and data logs; perform QC evaluations (NGS/Sanger) on generated libraries.

Skills

Library construction

Sequence diversity design

Project management

Documentation & QC

Scientific communication

Education

PhD in Molecular Biology/Biochemistry/Biotechnology

MS with 5+ years industry experience in antibody engineering

Tools

NGS data analysis software

Job description

Antibody Design Labs in San Diego is seeking a Research Scientist specializing in Molecular Biology and Antibody Engineering to lead library construction programs, drive sequence diversity design, and manage timelines to deliver high-quality discovery services in a fast-paced CRO setting.

You will collaborate on phage/yeast display libraries, oversee QC and documentation, and contribute to experimental design and client communication.