MES Engineer: Drive Opcenter MES for Operations

Biopharma Careers; Jaffrey (NH); On-site; USD 116,000 - 175,000; Full time

Benefits offered by this job

Health insurance

Paid time off (PTO)

Retirement contributions

Job summary

MilliporeSigma in Jaffrey, NH seeks a MES Engineer to support and improve Siemens Opcenter MES, providing day-to-day user support, configuration updates, and coordination with IT and cross-functional teams to align MES with site operations, quality, and compliance requirements.

The role collaborates with site SMEs, Operations, Quality, Validation, Automation, IT, and global digital teams, including potential future MES expansion and change-management activities.

Qualifications

• Bachelor’s degree in STEM, engineering, computer science, or related field.
• 5+ years of manufacturing experience.
• 2+ years supporting manufacturing, OT, MES, or related digital systems in production.
• Basic knowledge of manufacturing process support and system troubleshooting.
• Knowledge of Siemens Opcenter MES configuration and integrations.

Responsibilities

• Perform MES modeling and configuration changes to address operational needs.
• Resolve workflow, reporting, and integration issues in MES with cross-functional teams.
• Work with IT to support issues impacting Production uptime.
• Support equipment and enterprise system interfaces by monitoring data flow.
• Lead change management activities for MES maintenance with cross-functional support.
• Perform change assessments and support qualification and validation activities.
• Create and maintain technical documentation aligned with GAMP and SDLC.
• Ensure MES activities comply with GxP, data integrity, and quality requirements.
• Partner with Operations, Quality, Validation, Automation, IT for continuous improvement.

Skills

Manufacturing experience

MES support

Cross-functional collaboration

Analytical troubleshooting

Education

Bachelor’s degree in STEM

Tools

Siemens Opcenter MES

SQL queries

SAP Business Objects

OPC UA connectivity

Job description

MilliporeSigma in Jaffrey, NH seeks a MES Engineer to support and improve Siemens Opcenter MES, providing day-to-day user support, configuration updates, and coordination with IT and cross-functional teams to align MES with site operations, quality, and compliance requirements.

The role collaborates with site SMEs, Operations, Quality, Validation, Automation, IT, and global digital teams, including potential future MES expansion and change-management activities.