AAV Manufacturing Lead for Gene Therapy Programs

Scorpion Therapeutics

North Carolina

On-site

USD 140,000 - 160,000

Full time

14 days+
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Benefits offered by this job

On-site in Durham, NC
Salary range $140K–$160K

Job summary

Scorpion Therapeutics in Durham, NC is seeking a Senior Scientist in Discovery & Translational Research to establish and execute research-grade AAV manufacturing for gene therapy programs. You will lead end-to-end production and collaborate cross-functionally to align material quality with development needs.

The role requires 5+ years in AAV production, hands-on experience, and strong documentation practices.

Qualifications

  • B.S. or M.S. in Molecular Biology, Cell Biology, Biochemistry, or related field.
  • 5+ years industry experience in AAV production, process development, or gene therapy research.
  • Hands-on expertise in upstream/downstream AAV processing, analytical characterization, and process troubleshooting.
  • Strong understanding of AAV quality attributes and testing coordination.
  • Experience establishing research-grade workflows and documentation.

Responsibilities

  • Independently perform all phases of AAV production including cell culture, transfection, purification, characterization, and release.
  • Optimize workflows.
  • Troubleshoot processes.
  • Collaborate with Discovery, Analytical Development, and CMC teams to ensure research material quality and alignment with development needs.
  • Maintain compliant laboratory operations.

Skills

AAV production
Process development
Analytical characterization
Troubleshooting
Documentation

Education

B.S./M.S. in Molecular Biology, Cell Biology or Biochemistry

Tools

AAV purification equipment
Analytical characterization techniques
Documentation systems

Job description

Scorpion Therapeutics in Durham, NC is seeking a Senior Scientist in Discovery & Translational Research to establish and execute research-grade AAV manufacturing for gene therapy programs. You will lead end-to-end production and collaborate cross-functionally to align material quality with development needs.

The role requires 5+ years in AAV production, hands-on experience, and strong documentation practices.

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