Mammalian Cell Culture Process Scientist

Teva; West Chester (Chester County); On-site; USD 120,000 - 170,000; Full time

Benefits offered by this job

Comprehensive health insurance

401(k) with employer match

Paid time off

Life and disability insurance

Job summary

Teva Pharmaceuticals in West Chester, PA, is seeking a Scientist to join the Cell Culture Process Development team within Biologics CMC. This hands-on, lab-based role focuses on designing and executing mammalian cell culture studies to develop scalable processes for therapeutic proteins.

You will collaborate across functions to translate data into process decisions, optimize media and feeding strategies, and contribute to IND/BLA supporting documentation, with opportunities to work on

Qualifications

• MS in Chemical/Biochemical Engineering, 6+ years or BS with 8+ years of experience.
• Strong hands-on experience in mammalian cell culture, media/feed development, and bioreactor operations.
• Hands-on experience with mammalian suspension cell culture and bioreactor-based process development for recombinant proteins or other biologics.
• Demonstrated ability to independently plan experiments, analyze complex data, troubleshoot technical challenges, and draw clear, defensible conclusions.
• Working knowledge of cell culture process fundamentals, including growth, metabolism, productivity, product quality, media and feed effects, and scale-dependent process behavior.
• Clear written and verbal communication skills and the ability to collaborate effectively in a matrixed, multidisciplinary environment.

Responsibilities

• Design, execute, analyze, and document mammalian cell culture experiments with strong scientific rationale.
• Develop and optimize cell culture and harvest process, media, and feeding strategies to improve process performance, robustness, productivity, and product quality.
• Operate and troubleshoot mammalian cell culture systems across scales, including shake flasks, high-throughput or automated bioreactors, bench-scale bioreactors, and pilot-scale equipment.
• Apply scale-up and scale-down principles to establish representative models and translate process knowledge toward clinical and commercial manufacturing.
• Use DOEs, multivariate analysis, data modeling and digital tools to identify critical process relationships and enable data-driven decisions.
• Integrate cell culture performance with analytical and product quality data to build mechanistic process understanding and inform control strategies.
• Contribute to process characterization, new technology evaluations, facility-fit assessments, as appropriate for program stage.
• Partner with Cell Line Development, Purification Process Development, Analytical Development, Manufacturing, Quality, Regulatory, and external collaborators to deliver integrated CMC outcomes.
• Communicate conclusions and recommendations through technical reports, protocols, presentations, and regulatory submission content, including IND and BLA sections.
• Promote safe laboratory practices, data integrity, high-quality documentation, continuous improvement, and an inclusive team environment.

Skills

Mammalian cell culture

Bioreactor operations

DOE / DoE

Data modeling

Data analysis

Team collaboration

cGMP knowledge

Education

MS/BS in Chemical/Biochemical Engineering or related field

Cell Biology background

Tools

Bioreactors

Automation platforms

JMP / SIMCA (DoE)

Job description

Teva Pharmaceuticals in West Chester, PA, is seeking a Scientist to join the Cell Culture Process Development team within Biologics CMC. This hands-on, lab-based role focuses on designing and executing mammalian cell culture studies to develop scalable processes for therapeutic proteins.

You will collaborate across functions to translate data into process decisions, optimize media and feeding strategies, and contribute to IND/BLA supporting documentation, with opportunities to work on