Cell Culture Process Development Scientist

Teva Pharmaceuticals; West Chester (Chester County); On-site; USD 110,000 - 150,000; Full time

Job summary

Teva Pharmaceuticals in West Chester, PA, is seeking a Scientist to join the Cell Culture Process Development team within Biologics CMC. The role focuses on designing and executing mammalian cell culture studies to develop robust, scalable processes for therapeutic proteins from development to commercialization.

The ideal candidate has a strong foundation in mammalian culture with 6+ years (BS) or 8+ years (MS) of experience, and will work across scales with high-throughput bioreactors,

Qualifications

• 6+ years (BS) or 8+ years (MS) experience in mammalian cell culture.
• Strong hands-on experience with media/feed development and bioreactors.
• Experience translating data into process decisions for biotech development.

Responsibilities

• Design and execute mammalian cell culture experiments with strong scientific rationale.
• Develop and optimize cell culture and harvest process, media, and feeding strategies to improve process performance, robustness, productivity, and product quality.
• Operate and troubleshoot mammalian cell culture systems across scales, including shake flasks, high-throughput or automated bioreactors, bench-scale bioreactors, and pilot-scale equipment.
• Apply scale-up and scale-down principles to establish representative models and translate process knowledge toward clinical and commercial manufacturing.
• Use DOEs, multivariate analysis, data modeling and digital tools to identify critical process relationships and enable data-driven decisions.
• Integrate cell culture performance with analytical and product quality data to build mechanistic process understanding and inform control strategies.
• Contribute to process characterization, new technology evaluations, facility-fit assessments, as appropriate for program stage.
• Partner with Cell Line Development, Purification Process Development, Analytical Development, Manufacturing, Quality, Regulatory, and external collaborators to deliver integrated CMC outcomes.
• Communicate conclusions and recommendations through technical reports, protocols, presentations, and regulatory submission content, including IND and BLA sections.
• Promote safe laboratory practices, data integrity, high-quality documentation, continuous improvement, and an inclusive team environment.

Skills

Mammalian cell culture

DOE

Data modeling

Scale-up/Scale-down

Education

M.S. or B.S. in Chemical/Biochemical Engineering or Cell Biology

Job description

Teva Pharmaceuticals in West Chester, PA, is seeking a Scientist to join the Cell Culture Process Development team within Biologics CMC. The role focuses on designing and executing mammalian cell culture studies to develop robust, scalable processes for therapeutic proteins from development to commercialization.

The ideal candidate has a strong foundation in mammalian culture with 6+ years (BS) or 8+ years (MS) of experience, and will work across scales with high-throughput bioreactors,