Formulation Scientist

BioSpace; Redmond (WA); On-site; USD 90,000 - 110,000; Full time

Benefits offered by this job

Free colleague meals during shift

Onsite massages Charis

Onsite gyms

Job summary

GenScript USA Inc/ProBio Inc. in Redmond, WA is seeking a Nanoparticle Formulation Scientist to advance lipid nanoparticle formulations for RNA delivery, focusing on mRNA, DNA, and related therapeutics.

You will develop methods, characterize particles, support production scale-up, and collaborate with IP and customers, writing protocols and reports, while maintaining a clean lab and working with a diverse team.

Qualifications

• Master or PhD in pharmaceutical science, chemistry, biochemistry, chemical engineering or related field, Master is preferred.
• Strong knowledge of lipid and polymeric nanoparticle delivery technologies
• >4 years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle formulation and characterization
• Extensive experience with production and analytical characterization of nanoparticles
• Proficiency in all molecular biology techniques for mRNA and protein expression (RT-PCR, ELISA, Western blot, Flow-cytometry, etc) and RNA-related analytics (ribogreen, gel electrophoresis, capillary electrophoresis, etc).
• Works collaboratively with team members to support each other
• Excellent communication and problem-solving skills
• A sense of humility and an eagerness to continue to learn and contribute to a supportive team

Responsibilities

• Develop new lipid nanoparticle formulations (lipid or other polymers) platform for mRNA, DNA, RNA, peptide delivery, to achieve targeted delivery for different disease needs
• Develop method for characterizing and evaluating physical characteristics for antibody decorated LNPs
• Process development for high throughput LNP preparation and downstream process to improve production efficiency
• Produce formulations for related RNA projects, supporting functional assays for in vitro evaluation
• Maintain relationships with customers, participate in scientific meetings or customer meetings
• Write study protocols, technical reports, and SOPs to support mRNA product development projects
• Interact with IP counsel to assist with patent prosecution
• Monitors supply inventory and identifies any products required
• Maintains work area, equipment, department and all storage areas in a clean, neat and orderly manner
• Perform other duties as needed

Skills

Lipid nanoparticle delivery

Molecular biology techniques

Team collaboration

Excellent communication

Education

Master/PhD in pharmaceutical science/chemistry/biochemistry/chemical engineering

Job description

About GenScript

Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation in biotech and healthcare by providing researchers and companies with the building blocks needed to develop groundbreaking treatments and products. Guided by its mission to Make People and Nature Healthier Through Biotechnology, and its role as a well-recognized biotechnology company, GenScript has a team of approximately 6,165 employees and has served more than 200,000 customers across over 100 countries and regions.

About GenScript

Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation in biotech and healthcare by providing researchers and companies with the building blocks needed to develop groundbreaking treatments and products. Guided by its mission to Make People and Nature Healthier Through Biotechnology, and its role as a well-recognized biotechnology company, GenScript has a team of approximately 6,165 employees and has served more than 200,000 customers across over 100 countries and regions. GenScript is looking for a highly motivated and scientifically rigorous Nanoparticle Formulation Scientist to join our RNA team. This position will focus on developing novel lipid nanoparticle formulations for RNA delivery.

Responsibilities

• Develop new lipid nanoparticle formulations (lipid or other polymers) platform for mRNA, DNA, RNA, peptide delivery, to achieve targeted delivery for different disease needs, like neuronal, brain, muscle, bone marrow cell, etc.
• Develop method for characterizing and evaluating physical characteristics for antibody decorated LNPs.
• Process development for high throughput LNP preparation and downstream process to improve production efficiency.
• Produce formulations for related RNA projects, supporting functional assays for in vitro evaluation.
• Maintain relationships with customers, participate in scientific meetings or customer meetings.
• Write study protocols, technical reports, and SOPs to support mRNA product development projects.
• Interact with IP counsel to assist with patent prosecution.
• Monitors supply inventory and identifies any products required.
• Maintains work area, equipment, department and all storage areas in a clean, neat and orderly manner.
• Perform other duties as needed.

Requirements

• Master or PhD's degree in pharmaceutical science, chemistry, biochemistry, chemical engineering or related field, Master is preferred
• Strong knowledge of lipid and polymeric nanoparticle delivery technologies
• >4 years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle formulation and characterization
• Extensive experience with production and analytical characterization of nanoparticles
• Proficiency in all molecular biology techniques for mRNA and protein expression (RT-PCR, ELISA, Western blot, Flow-cytometry, etc) and RNA-related analytics (ribogreen, gel electrophoresis, capillary electrophoresis, etc).
• Works collaboratively with team members to support each other
• Excellent communication and problem-solving skills
• A sense of humility and an eagerness to continue to learn and contribute to a supportive team

Benefit

• Medical Insurance/ Vision Insurance/ Dental Insurance
• 401(k) & Retirement Savings Plan (RSP)
• Short Term Disability Insurance
• New Child Leave
• Paid Time Off
• Paid Company Holidays per year
• Paid Sick Days (earned based on hours worked)
• Compassionate Leave
• Jury Duty Leave
• Float day
• Personal days

Perks

• Free colleague meals during shift
• Onsite massages Charis
• Onsite gyms

Compensation

Salary range: $90,000 – $110,000 total compensation, including bonus, depending on experience and qualifications.

Benefits

Benefits include medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and company holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.

Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.