LNP Formulation Scientist – Hybrid Role

Sanofi Group; Waltham (MA); Hybrid; USD 120,000 - 180,000; Full time

Benefits offered by this job

Healthcare benefits

14 weeks parental leave

Hybrid work model

Job summary

Sanofi in Waltham, MA, is seeking a Scientist/Engineer to lead formulation optimization of mRNA-LNP formulations and to drive developability studies within the DP Group. You will design multi-component experiments, coordinate cross-functional teams, and develop initial processes while ensuring quality documentation and data integrity.

The role requires strong background in formulation and process development, with experience in LNP techniques and analytical characterization.

Qualifications

• Requires strong formulation and process development background.
• Experience designing multi-component formulation experiments is essential.
• Proven ability to interpret complex data and guide development strategy.

Responsibilities

• Lead formulation optimization and understanding of LNP formulations for mRNA.
• Collaborate with Research to transfer new LNP formulations into CMC development.
• Design small-scale experiments to study developability of new LNPs.
• Compile Developability packages for new formulations.
• Develop initial formulation processes for new LNP formulations.
• Plan studies to assess stability of new formulations.
• Perform in-process drug product characterization.
• Apply analytical methods to characterize formulations and troubleshoot.
• Coordinate advanced LNP characterization with Analytical Sciences.
• Support troubleshooting of technical formulation/processing issues.
• Document study setup, results and conclusions in electronic lab notebooks.
• Summarize study progress and data to scientific teams.

Skills

Experiment design

Data analysis

Cross-functional communication

Education

Bachelor's in Engineering, Pharmaceutical Sciences, or Chemistry related science discipline

Master's in Engineering, Pharmaceutical Sciences, or Chemistry related science discipline

Ph.D. in Engineering, Pharmaceutical Sciences, or Chemistry related science discipline

Tools

LNP formulation

Analytical techniques

Job description

Sanofi in Waltham, MA, is seeking a Scientist/Engineer to lead formulation optimization of mRNA-LNP formulations and to drive developability studies within the DP Group. You will design multi-component experiments, coordinate cross-functional teams, and develop initial processes while ensuring quality documentation and data integrity.

The role requires strong background in formulation and process development, with experience in LNP techniques and analytical characterization.