Lead Translational Quantitative Pharmacology Scientist

Biopharma Careers; Billerica (MA); On-site; USD 142,000 - 215,000; Full time

Job summary

Biopharma Careers is seeking a Principal Scientist in Translational Quantitative Pharmacology to lead model-informed drug development efforts. You will develop quantitative systems pharmacology platform models and manage multiple collaborations across R&D. The role requires communicating complex modeling results to diverse teams and advancing immunology and oncology programs. Expect travel up to 20%.

Qualifications

• PhD in Pharmacokinetics, Pharmaceutical Sciences, or related field.
• At least 5 years in industry or academia applying modeling to biological problems.
• Travel up to 20% domestically and internationally.

Responsibilities

• Develop QSP models to inform compound progression decisions across immunology and oncology pipelines.
• Perform human PK predictions and quantitative DDI predictions; design and analyze preclinical PK/PD data.
• Develop models to understand toxicological signals and guide project decisions.
• Explain modeling concepts to colleagues across disciplines and contribute to toolbox development.
• Present analysis outcomes to cross-functional teams and leadership.

Skills

QSP knowledge

MATLAB/SimBiology

NONMEM

R

Monolix

PBPK modeling

Mentoring

Modeling simulations

Education

PhD in Pharmacokinetics

Biomedical Engineering

Applied Mathematics

Tools

MATLAB

SimBiology

Simcyp

GastroPlus

R

Monolix

NONMEM

Job description

Biopharma Careers is seeking a Principal Scientist in Translational Quantitative Pharmacology to lead model-informed drug development efforts. You will develop quantitative systems pharmacology platform models and manage multiple collaborations across R&D. The role requires communicating complex modeling results to diverse teams and advancing immunology and oncology programs. Expect travel up to 20%.