Lead Translational PK/PD Modeling Scientist (On-Site)

Regeneron Pharmaceuticals, Inc.; Village of Tarrytown (NY); On-site; USD 160,000 - 230,000; Full time

Job summary

Regeneron is seeking a Principal Scientist of Translational PK/PD Modeling to develop quantitative and mechanistic models that support target biology understanding, modality optimization, and early clinical dose selection. You will lead model development across preclinical to early clinical programs.

The role requires a PhD or MS with strong modeling expertise; experience with NONMEM, Monolix, MATLAB; PBPK knowledge is preferred. On-site in Tarrytown, NY, four days per week.

Qualifications

• PhD or MS with strong quantitative PK/PD modelling background.
• Industry experience in modeling and simulation required.
• Knowledge of biologics and PBPK modelling preferred.

Responsibilities

• Create and implement PK/PD models for preclinical to clinical translation.
• Guide dose predictions for early clinical development.
• Support cross-disciplinary teams in pharmacology study design.
• Contribute to strategic direction of modeling sciences.

Skills

PK/PD modeling

Quantitative analysis

NONMEM

Monolix

MATLAB

PBPK modelling

Biologics knowledge

Education

PhD in PK/Pharmaceutical sciences/engineering/applied mathematics

MS in PK/Pharmaceutical sciences/engineering/applied mathematics

Tools

NONMEM

Monolix

MATLAB

Job description

Regeneron is seeking a Principal Scientist of Translational PK/PD Modeling to develop quantitative and mechanistic models that support target biology understanding, modality optimization, and early clinical dose selection. You will lead model development across preclinical to early clinical programs.

The role requires a PhD or MS with strong modeling expertise; experience with NONMEM, Monolix, MATLAB; PBPK knowledge is preferred. On-site in Tarrytown, NY, four days per week.