Senior Translational PK/PD Modeling Scientist

Regeneron Pharmaceuticals

Tarrytown (GA)

Sur place

USD 151 000 - 246 000

Plein temps

14 jours+

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Résumé du poste

Regeneron Pharmaceuticals seeks a Principal Scientist of Translational PK/PD Modeling to develop quantitative and mechanistic PK/PD models guiding preclinical-to-early clinical translation and first-in-human dose selection. The role informs target biology and therapeutic modality optimization within an on-site team in our Tarrytown, NY office.

You will lead modeling and simulation efforts, collaborate with Clinical Pharmacology, and contribute to study design while mentoring others and

Qualifications

  • Ph.D. with 4+ years of PK/PD modeling experience or MS with 6+ years in pharma/biotech.
  • Experience applying quantitative and mechanism-based PK/PD modeling to therapeutics.
  • Industry experience in pharmacometrics or related field.

Responsabilités

  • Develops quantitative and mechanistic PK/PD models for preclinical to early clinical translation.
  • Contributes to advancing modeling and simulation sciences strategy.
  • Supports project teams with in vitro/in vivo quantitative pharmacology studies.
  • Summarizes analyses for multidisciplinary teams and communicates findings.
  • Keeps up with emerging literature and collaborates with Clinical Pharmacology and R&D teams.
  • Shares learnings and develops best practices across disease areas.
  • Mentors others and presents work at meetings and journals.
  • Travels as needed to collaborate with teams.

Connaissances

Quantitative PK/PD modeling
Translational pharmacology
Modeling strategy

Formation

Ph.D. in pharmacokinetics/pharmaceutical sciences/engineering
M.S. in related discipline

Outils

Monolix
Phoenix NLME
NONMEM
MATLAB/SimBiology

Description du poste

Regeneron Pharmaceuticals seeks a Principal Scientist of Translational PK/PD Modeling to develop quantitative and mechanistic PK/PD models guiding preclinical-to-early clinical translation and first-in-human dose selection. The role informs target biology and therapeutic modality optimization within an on-site team in our Tarrytown, NY office.

You will lead modeling and simulation efforts, collaborate with Clinical Pharmacology, and contribute to study design while mentoring others and

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