Lead Scientist, Proteomics & Metabolomics Core

University of Virginia; Charlottesville (VA); On-site; USD 110,000 - 150,000; Full time

Job summary

The W.M. Keck Biomedical Mass Spectrometry Lab at the University of Virginia seeks a Senior Scientist to expand proteomics and metabolomics efforts using state-of-the-art instruments to support research across basic science, Cancer Center, and clinical projects.

The role requires expert hands-on biomedical science experience with MS and chromatography, and data analysis using Proteome Discoverer, Scaffold, and related software.

Qualifications

• Possess prior experience in qualitative and quantitative proteomics and metabolomics technology and nano‑liquid chromatography and mass spectrometry (LC‑MS; on Orbitrap Fusion, Orbitrap Astral, and/or Orbitrap ID‑X).
• The candidate should be familiar with the entire metabolomics and/or proteomics pipeline (including sample preparation, LC and MS operation, and data analysis) and must be able to conduct independent projects.
• Manage multiple projects between multiple laboratories.
• Demonstrate scientific productivity and have excellent oral and written communication skills.
• Demonstrate attention to detail and ability to learn new technologies, flexibility and time management skills.

Responsibilities

• Operate and maintain advanced mass spectrometers (Orbitrap ID‑X – Vanquish Neo and Orbitrap Astral Zoom – Evosep Eno).
• Support the director through sample preparation and data analysis using advanced software packages (Proteome Discoverer, Compound Discoverer, Scaffold, etc).
• Advance institutional goals in proteomic and metabolomic profiling and translational research.
• Collaborate across laboratories and manage multiple projects.

Skills

Proteomics

Metabolomics

Mass spectrometry

Chromatography

Data analysis

Independent projects

Communication skills

Time management

Laboratory management

Education

Ph.D. in Mass Spectrometry

Tools

Proteome Discoverer

Compound Discoverer

Scaffold

MS Dial

MetaboAnalyst

Orbitrap Fusion

Orbitrap Astral

Orbitrap ID-X

Thermo instruments

Job description

The W.M. Keck Biomedical Mass Spectrometry Lab at the University of Virginia seeks a Senior Scientist to expand proteomics and metabolomics efforts using state-of-the-art instruments to support research across basic science, Cancer Center, and clinical projects.

The role requires expert hands-on biomedical science experience with MS and chromatography, and data analysis using Proteome Discoverer, Scaffold, and related software.