Proteomics Lead Scientist: Advanced LC-MS/MS & Data

University of Kentucky; Lexington (VA); On-site; USD 73,861 - 121,888; Full time

Job summary

The University of Kentucky invites applications for a Lead Proteomics Scientist to lead the Mass Spectrometry Core. You will develop advanced proteomics workflows, oversee data quality, and collaborate with investigators across disciplines to design experiments and deliver high-impact data.

This role requires a PhD and 5+ years of experience in LC-MS/MS proteomics, with hands-on expertise in high-resolution mass spectrometry, data analysis, and method development.

Qualifications

• : PhD required.
• : 5+ years related proteomics experience.
• : Experience with LC-MS/MS and proteomics workflows.
• : Strong data interpretation and collaboration skills.
• : Ability to lead a core facility and manage multiple projects.

Responsibilities

• Develop and implement discovery, quantitative, targeted, and specialized proteomics workflows
• Design and optimize LC-MS/MS methods and data analysis pipelines
• Operate, maintain, and troubleshoot mass spectrometry instrumentation
• Conduct proteomics experiments including sample prep and quantitative analyses
• Consult with investigators on study design and analytical strategies
• Support manuscript preparation, grant applications, and collaborative efforts
• Evaluate emerging technologies and incorporate into core services
• Maintain quality control and laboratory compliance

Skills

LC-MS/MS proteomics

High-resolution MS

Proteomics data analysis

Experimental design & data

Multidisciplinary collaboration

Project management

Scientific writing

Innovative technologies

Education

PhD

Tools

Orbitrap mass spectrometers

Thermo Scientific instruments (Orbitrap Exploris/Ascend/Altis)

Job description

The University of Kentucky invites applications for a Lead Proteomics Scientist to lead the Mass Spectrometry Core. You will develop advanced proteomics workflows, oversee data quality, and collaborate with investigators across disciplines to design experiments and deliver high-impact data.

This role requires a PhD and 5+ years of experience in LC-MS/MS proteomics, with hands-on expertise in high-resolution mass spectrometry, data analysis, and method development.