Lead Scientist, Mammalian Expression & Cell Line Engineering

Amgen Inc. (IR); Thousand Oaks (CA); On-site; USD 124,000 - 167,000; Full time

Benefits offered by this job

Stock-based long-term incentives

Comprehensive benefits package

Flexible work models where possible

Job summary

Amgen Inc. in Thousand Oaks seeks a Senior Scientist to lead mammalian expression and cell line engineering for biologics discovery. You will help develop expression platforms, optimize constructs and workflows, and drive data-driven improvements in productivity and quality.

The role requires deep technical expertise, cross-functional collaboration, and mentorship to junior staff, with a focus on scalable, automation-enabled processes across programs.

Qualifications

• Experience with mammalian expression systems and cell line engineering.
• Ability to develop and optimize expression platforms and workflows.
• Experience driving automation-enabled biology and high-throughput strategies.

Responsibilities

• Serve as a technical expert in mammalian expression and cell line engineering, contributing to strategy across programs.
• Develop and implement innovative approaches to improve productivity, product quality, and speed.
• Evaluate and implement new technologies and automation solutions to enhance workflow robustness and throughput.
• Collaborate with cross-functional teams to advance discovery programs and mentor junior scientists.

Skills

Mammalian expression

Cell line engineering

Data-driven optimization

Cross-functional collaboration

Mentorship

Education

PhD/MD/PharmD or Masters with postdoc experience

Job description

Amgen Inc. in Thousand Oaks seeks a Senior Scientist to lead mammalian expression and cell line engineering for biologics discovery. You will help develop expression platforms, optimize constructs and workflows, and drive data-driven improvements in productivity and quality.

The role requires deep technical expertise, cross-functional collaboration, and mentorship to junior staff, with a focus on scalable, automation-enabled processes across programs.