Senior Scientist: Mammalian Expression & Cell Line Engineering

Amgen; Thousand Oaks (CA); On-site; USD 180,000 - 230,000; Full time

Benefits offered by this job

Stock-based long-term incentives

Discretionary annual bonus

Flexible work models

Job summary

Amgen’s Protein Therapeutics group in California seeks a Principal Scientist to lead mammalian expression and cell line engineering for next-generation protein therapeutics. This senior IC role emphasizes data-driven decision making, innovation, and collaboration across programs in oncology, inflammation, and rare disease.

No direct reports are required. The role requires a PhD with extensive postdoctoral experience or equivalent, strong publication/patent record, and the ability to drive

Qualifications

• PhD or equivalent with relevant postdoctoral experience.
• Experience in mammalian expression and cell line engineering is required.
• Ability to drive innovation and data-driven decision making.

Responsibilities

• Provide scientific leadership in mammalian expression and cell line engineering.
• Lead high-throughput expression workflows and optimization of protein therapeutics.
• Collaborate with cross-functional teams to advance programs and publish findings.

Skills

Mammalian expression

Cell line engineering

Automation

Data-driven decisions

Education

PhD in biology/biotech

Job description

Amgen’s Protein Therapeutics group in California seeks a Principal Scientist to lead mammalian expression and cell line engineering for next-generation protein therapeutics. This senior IC role emphasizes data-driven decision making, innovation, and collaboration across programs in oncology, inflammation, and rare disease.

No direct reports are required. The role requires a PhD with extensive postdoctoral experience or equivalent, strong publication/patent record, and the ability to drive