Lead, Peptidomimetic R&D Chemistry & Conjugates

BioSpace; Town of Mount Pleasant (NY); On-site; USD 176,000 - 287,000; Full time

Job summary

Regeneron is seeking an Associate Director (Peptidomimetics), R&D Chemistry, to lead the Peptidomimetic group and drive SAR and bioconjugation strategies for antibody-conjugated therapeutics. The role requires a PhD in peptide/synthetic organic chemistry and 10+ years of industry experience.

This is an on-site position based in Hawthorne, NY, with occasional travel to the Tarrytown facility. The successful candidate will guide cross-functional teams and shape a future-focused drug discovery

Qualifications

• Ph.D. in peptide and/or synthetic organic chemistry or a related field.
• Extensive drug discovery experience with antibody-targeted peptidomimetic drug modalities.
• Experience leading teams and building cross-functional project teams.
• Strong leadership, collaboration, and communication to guide cross-functional groups.

Responsibilities

• Directly supervise and manage day-to-day activities of the R&D Chemistry Peptidomimetic group.
• Perform medicinal chemistry inspired and SAR-driven generation of novel peptidomimetic drug modalities.
• Troubleshoot and optimize peptide potency and stability using standard peptide-based principles and bioconjugation strategies.
• Champion and lead the R&D Chemistry Peptidomimetic efforts on internal/external project teams.
• Identify new strategies and technologies to improve synthesis and bioconjugation of peptidomimetic drug modalities.
• Interact with cross-functional teams and represent the group in meetings and reviews.

Skills

Peptidomimetic chemistry

Medicinal chemistry

Synthetic organic chemistry

Education

PhD in peptide and/or synthetic organic chemistry

Tools

Bioconjugation techniques

Ala scans

Job description

Regeneron is seeking an Associate Director (Peptidomimetics), R&D Chemistry, to lead the Peptidomimetic group and drive SAR and bioconjugation strategies for antibody-conjugated therapeutics. The role requires a PhD in peptide/synthetic organic chemistry and 10+ years of industry experience.

This is an on-site position based in Hawthorne, NY, with occasional travel to the Tarrytown facility. The successful candidate will guide cross-functional teams and shape a future-focused drug discovery