Lead PAT Scientist, Analytical R&D

ABBVIE; North Chicago (IL); On-site; USD 125,000 - 237,000; Full time

Job summary

AbbVie in North Chicago, IL is seeking a Principal Research Scientist I in Analytical R&D to lead PAT strategy for synthetic molecule programs, guiding drug substance and product development from early development through validation and transfer.

The role requires deep expertise in chemometrics, spectroscopic PAT methods, data analysis, and cross‑functional collaboration with Process Engineering, QA, and Regulatory.

Qualifications

• Extensive PAT method development across development lifecycle.
• Lead and mentor a small PAT team.
• Integrate chemometrics with process understanding.
• Collaborate with cross-functional partners to drive tech transfer.

Responsibilities

• Mentor, supervise, and develop a small team of PAT scientists; set priorities and deliver across programs.
• Create and maintain an integrated PAT strategy for drug substance and drug product programs.
• Lead PAT feasibility assessments, method development, validation, and technology transfer.

Skills

PAT strategy

Chemometrics

Spectroscopic PAT

Multivariate analysis

Team leadership

Education

PhD in Analytical Chemistry / Chemical Engineering

MS in Analytical Chemistry

BS in Chemistry or related field

Tools

Unscrambler

PLS_Toolbox

SIMCA

MATLAB

Python

R

Job description

AbbVie in North Chicago, IL is seeking a Principal Research Scientist I in Analytical R&D to lead PAT strategy for synthetic molecule programs, guiding drug substance and product development from early development through validation and transfer.

The role requires deep expertise in chemometrics, spectroscopic PAT methods, data analysis, and cross‑functional collaboration with Process Engineering, QA, and Regulatory.