Lead, Lentiviral Vector Formulation & Drug Product

Eli Lilly and Company; Boston (MA); On-site; USD 141,000 - 231,000; Full time

Benefits offered by this job

401(k) plan

Pension

Vacation benefits

Medical, dental, vision benefits

Flexible benefits

Life insurance

Well-being programs

Job summary

Eli Lilly and Company in Boston invites an experienced leader in lentiviral vector formulation and drug product development to join the Cell and Gene Therapy program. The role focuses on LVV formulation, fill‑finish process development, technology transfer, and evolving manufacturing strategies across in vivo CAR‑T programs.

You'll contribute to regulatory submissions, mentor scientists, and drive scalable, phase‑appropriate processes while collaborating across GMP facilities and CDMOs in a

Qualifications

• Ph.D. in Pharmaceutical Sciences, Chemical Engineering, Biochemical Engineering, Bioengineering, Biochemistry, Biology, or related field with 5+ years of industry experience; or a master’s with 10+ years; or a bachelor’s with 15+ years.
• Significant experience in formulation, drug product, fill‑finish, and/or process development for viral vectors or other complex biologic products, with direct experience in lentiviral vector development.

Responsibilities

• Define and lead drug product development strategies across multiple in vivo CAR‑T programs, establishing robust and scalable approaches.
• Lead formulation development and optimization for viral vector drug products, focusing on stability, potency, manufacturability, and compatible clinical presentation.
• Lead drug product process development, including final filtration, fill‑finish, container closure selection, and storage/shipping strategies.
• Develop phase‑appropriate manufacturing processes and scale‑down models for characterization, transfer, and lifecycle management.
• Lead technology transfer to internal sites and/or external CDMOs as technical lead for formulation, fill‑finish, and manufacturing.
• Support regulatory submissions (INDs, IMPDs, BLAs, MAAs) and respond to health authority questions.
• Communicate development strategy and risk mitigation plans to program teams and senior leadership.
• Provide scientific leadership and mentorship to scientists and engineers; build drug product capabilities.
• Maintain awareness of literature and regulatory expectations; identify innovative tech to improve quality and speed to supply.

Skills

Formulation development

Drug product development

Viral vectors

Lentiviral vector

Technology transfer

Regulatory strategy

Leadership

Cross-functional collaboration

Education

Ph.D. in Pharmaceutical Sciences or related field

Or master's with 10+ years experience

Job description

Eli Lilly and Company in Boston invites an experienced leader in lentiviral vector formulation and drug product development to join the Cell and Gene Therapy program. The role focuses on LVV formulation, fill‑finish process development, technology transfer, and evolving manufacturing strategies across in vivo CAR‑T programs.

You'll contribute to regulatory submissions, mentor scientists, and drive scalable, phase‑appropriate processes while collaborating across GMP facilities and CDMOs in a