Senior Principal Scientist, QC — Gene Therapy Startup

Eli Lilly and Company; Lebanon (IN); On-site; USD 66,000 - 172,000; Full time

Benefits offered by this job

Company bonus

Comprehensive benefits package

Job summary

Eli Lilly and Company in Lebanon, Indiana, is building a state-of-the-art QC lab for gene therapy products, including viral and non-viral vectors, with a focus on data integrity and regulatory readiness. The role supports method transfer, validation, and routine testing as the site scales for clinical and commercial supply.

This position collaborates across Manufacturing Science, Analytical Development, QA, and external partners, mentoring lab staff and ensuring testing readiness as the facility

Qualifications

• Bachelor's degree in chemistry, biochemistry, molecular biology, or related science.
• 7+ years of advanced therapy experience in gene therapy or related modalities.
• Experience with analytical testing in a commercialization/manufacturing environment.
• Proficient in root cause analysis and laboratory investigations.

Responsibilities

• Serve as a site SME for gene therapy analytical methods and support the QC team.
• Perform method transfer, qualification, and validation for products from acquisitions and internal development.
• Execute assays for in‑process, release, and stability testing with GMP data integrity.
• Support site readiness, equipment/method readiness, and lifecycle management of methods.
• Collaborate with Technical Services/Manufacturing Science, Analytical Development, QA, and external partners.
• Prepare and review technical documents; assist inspections and train staff.

Skills

Root Cause Analysis

Technical SME

Cross-functional collaboration

Analytical testing

Education

Bachelor's degree in chemistry, biochemistry, molecular biology, or related science

Tools

ddPCR/qPCR

ELISA

Capsid characterization

Cell-based potency assays

Job description

Eli Lilly and Company in Lebanon, Indiana, is building a state-of-the-art QC lab for gene therapy products, including viral and non-viral vectors, with a focus on data integrity and regulatory readiness. The role supports method transfer, validation, and routine testing as the site scales for clinical and commercial supply.

This position collaborates across Manufacturing Science, Analytical Development, QA, and external partners, mentoring lab staff and ensuring testing readiness as the facility