Lead Lentiviral Vector Cell Line Developer

Asimov; Boston (MA); On-site; USD 180,000 - 240,000; Full time

Job summary

Asimov in Boston, MA is seeking a Principal Scientist to lead the Lentiviral Vector CLD team, steering the platform roadmap and developing stable producer cell lines for lentiviral vector therapeutics.

You will mentor scientists, partner with our commercial team to present capabilities, and drive cross-functional project plans while advancing workflows and scale-up for GMP activities.

Qualifications

• MS/PhD in Biological Engineering, Virology, Cell Biology, Molecular Biology or related field.
• 10+ years of hands-on biopharma experience, including 6+ years in lentiviral vector producer or packaging cell line development for GLP/GMP.
• 2+ years managing direct reports and providing technical guidance.
• Proven track record balancing bench leadership with platform strategy and roadmapping.
• Experience communicating technical work to external stakeholders and translating needs into technical plans.
• Publications/patents/conference presentations demonstrating external communication of scientific work.

Responsibilities

• Set and steer the scientific roadmap for the Lentiviral Vector CLD platform.
• Lead lentiviral vector stable producer cell line development including transfection, pool generation, cloning, screening, characterization and cell banking.
• Serve as primary CLD technical contact on customer and commercial projects; translate customer requirements into executable CLD plans.
• Provide technical leadership and mentorship to scientists; manage direct reports and ensure robust experimental design and data record‑keeping.
• Represent CLD on cross‑functional and leadership teams; communicate progress, risks, and plans clearly.
• Support innovation through new workflows and applications; advance viral vector production methods and product quality attributes.
• Collaborate with Synthetic Biology and Process Development teams across projects and scale-up efforts.
• Design experiments, analyze data, troubleshoot, and maintain detailed records.
• Represent CLD externally through publications and presentations.

Skills

Leadership

Project management

Data analysis

Scientific communication

GLP/GMP experience

Education

MS/PhD in Biological Engineering, Virology, Cell Biology, Molecular Biology

Tools

Ambr system

Benchtop bioreactor

Job description

Asimov in Boston, MA is seeking a Principal Scientist to lead the Lentiviral Vector CLD team, steering the platform roadmap and developing stable producer cell lines for lentiviral vector therapeutics.

You will mentor scientists, partner with our commercial team to present capabilities, and drive cross-functional project plans while advancing workflows and scale-up for GMP activities.