Viral Vector Process Engineer – Scale-Up & Transfer

Asimov; Boston (MA); On-site; USD 120,000 - 160,000; Full time

Job summary

Asimov in Boston, MA is seeking a Scientist I/II, Viral Vector Process Development to advance gene therapies. You will execute LV and AAV vector-based process development, optimize upstream workflows, and collaborate across teams to transfer technology to partners.

The role covers media/feed optimization, bioreactor scale-up (Ambr15/Ambr250), analytical assay development, and product quality assessment, with a strong emphasis on rigorous documentation and reproducible workflows.

Qualifications

• Bachelor's in Biological Engineering, Chemical Engineering, Cell Biology, Molecular Biology, or related field with 6–8 years of hands-on industry viral vector process development.
• MS with 3–4 years or PhD with 0–2 years of equivalent experience accepted.
• Mammalian cell culture experience and aseptic technique.
• Experience with Ambr15, Ambr250 and benchtop scale viral vector bioreactor processes.
• Strong organizational skills and ability to follow standardized workflows.
• Experience in cell line development and technology transfer in pharma.

Responsibilities

• Drive media/feed optimization, bioreactor process development, scale-up and characterization (Ambr15, Ambr250, benchtop).
• Coordinate technology transfer of upstream processes to external partners.
• Create and optimize throughput and robustness of workflows for cell line characterization and assays.
• Collaborate with Viral Vector and Biologics teams on clone screening studies in bioreactor systems.
• Author, review and approve process development reports and transfer protocols.
• Support downstream processing, purification and product quality assessment with analytics.
• Represent the PD team on cross-functional projects and communicate results and plans.

Job description

Asimov in Boston, MA is seeking a Scientist I/II, Viral Vector Process Development to advance gene therapies. You will execute LV and AAV vector-based process development, optimize upstream workflows, and collaborate across teams to transfer technology to partners.

The role covers media/feed optimization, bioreactor scale-up (Ambr15/Ambr250), analytical assay development, and product quality assessment, with a strong emphasis on rigorous documentation and reproducible workflows.