Lead, Early-Phase Cardiometabolic Clinical Development

amgen; United States; On-site; USD 275,000 - 371,773; Full time

Benefits offered by this job

Retirement plan

Medical, dental, vision coverage

Stock-based incentives

Award-winning time-off plans

Flexible work models

Job summary

Amgen is seeking a Clinical Development Director to lead the early phase clinical development of cardiometabolic/general medicine compounds from first-in-human to proof-of-concept in the United States. You will guide protocol development, study start-up, data review, monitoring and analysis, collaborating with cross-functional teams to ensure rigorous trial execution.

The role emphasizes leadership, collaboration, and strategic input across Regulatory, Safety and Clinical groups, with

Qualifications

• MD or DO degree from an accredited medical school
• 2 years of industry or academic/basic sciences/clinical research experience
• Board certification or eligible in Internal Medicine, Cardiology, or Endocrinology

Responsibilities

• Contribute to early clinical development strategy for cardiometabolic/general medicine candidates
• Prepare clinical development plans, protocols, and regulatory submissions
• Review safety, efficacy, pharmacodynamics and pharmacokinetic data
• Collaborate with Amgen Precision Medicine, Research, Late Development, Regulatory, Safety and Commercial teams
• Engage with external experts to provide biomedical guidance to Early Development teams
• Contribute to evaluation of external licensing or partnering opportunities

Skills

Leadership

Communication

Cross-functional collaboration

Presentation skills

Education

MD/DO degree

Residency in Internal Medicine

Board certification or eligibility (Internal Medicine/Cardiology/Endocrinology)

Job description

Amgen is seeking a Clinical Development Director to lead the early phase clinical development of cardiometabolic/general medicine compounds from first-in-human to proof-of-concept in the United States. You will guide protocol development, study start-up, data review, monitoring and analysis, collaborating with cross-functional teams to ensure rigorous trial execution.

The role emphasizes leadership, collaboration, and strategic input across Regulatory, Safety and Clinical groups, with