Director of Early Cardiometabolic Clinical Development

BioSpace; Washington (District of Columbia); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Retirement plan

Medical/dental/vision coverage

Life insurance

Disability insurance

Flexible spending accounts

Bonus program

Stock-based incentives

Generous paid time off

Flexible work models

Job summary

Amgen in Washington, DC seeks a Clinical Development Director to lead the early phase clinical development of cardiometabolic and general medicine programs from first-in-human to proof-of-concept. You will design trials, write protocols, and collaborate with regulatory, safety, and translational teams to ensure high-quality data and timely execution.

The role requires MD/DO with 3+ years in drug development, leadership in cross-functional settings, and a track record in early-stage studies and

Qualifications

• MD or DO degree from an accredited medical school.
• 2 years of industry or academic/basic sciences/clinical research experience.
• Board certification or eligible (Internal Medicine, Cardiology, or Endocrinology).
• Residency training in Internal Medicine and relevant subspecialty.
• Understanding of cardiometabolic and general medicine pathophysiology.
• Experience in basic research and/or clinical trial methodology.
• 3+ years of relevant drug development experience in pharma/academia.
• Experience collaborating with pharmaceutical sponsors.

Responsibilities

• Contribute to the design and implementation of the early clinical development strategy for cardiometabolic/general medicine therapeutic candidates.
• Contribute to the preparation of clinical development plans, clinical study protocols, informed consents, Investigator Brochures, and Ethics Committee and regulatory submissions.
• Review and evaluate clinical study safety, efficacy, pharmacodynamic and pharmacokinetic data.
• Contribute to the strategy and use of clinical biomarkers to facilitate drug development.
• Actively collaborate with Amgen Precision Medicine, Research, Late Development, Regulatory, Safety and Commercial colleagues.
• Contribute to the evaluation of external licensing or partnering opportunities within the cardiometabolic/general medicine therapeutic areas.
• Collaborate with external experts to provide biomedical expertise and strategic guidance to cardiometabolic/general medicine Early Development teams.

Skills

Leadership

Cross-functional collaboration

Strategic thinking

Communication skills

Education

MD or DO degree

Board-certified or eligible (Internal Medicine/Cardiology/Endocrinology)

Residency in Internal Medicine with subspecialty

3+ years in drug development (pharma/academia)

Job description

Amgen in Washington, DC seeks a Clinical Development Director to lead the early phase clinical development of cardiometabolic and general medicine programs from first-in-human to proof-of-concept. You will design trials, write protocols, and collaborate with regulatory, safety, and translational teams to ensure high-quality data and timely execution.

The role requires MD/DO with 3+ years in drug development, leadership in cross-functional settings, and a track record in early-stage studies and