Lead Analytical Scientist, Dissolution & Formulation

Vertex Pharmaceuticals Incorporated; Boston (MA); On-site; USD 140,800 - 211,200; Full time

Benefits offered by this job

On-site role

Annual bonus eligibility

Equity awards

Inclusive benefits

Job summary

Vertex Pharmaceuticals is seeking a Principal Research Scientist to join the Dissolution Team within the Formulation Development Department. This role offers an opportunity to contribute to scientific capabilities while growing into a leadership position on the team.

The successful candidate will lead dissolution studies, design validation protocols, author regulatory submissions, and drive cross-functional collaboration to support late-stage programs and regulatory filings.

Qualifications

• Ph.D. in Chemistry, Chemical Engineering or Pharmaceutical Chemistry with 4–7 years experience, or Master's with 7+ years, or Bachelor's with 10+ years
• Proven ability to learn and apply new scientific concepts and techniques
• Strong interpersonal and communication skills to foster collaboration across teams
• Proven ability to lead, mentor, and inspire team members with a desire to grow into a managerial role

Responsibilities

• Lead dissolution studies to support formulation development and regulatory submissions
• Design validation protocols in compliance with ICH and FDA guidelines
• Author dissolution sections for regulatory submissions
• Identify critical factors/parameters essential for developing and validating robust dissolution methods
• Mentor and guide team members to support professional growth and high performance
• Engage in data-driven discussions to drive decision making and outcomes

Skills

Leadership

Teamwork

Communication

Education

Ph.D. in Chemistry/Chemical Engineering/Pharmaceutical Chemistry

Job description

Vertex Pharmaceuticals is seeking a Principal Research Scientist to join the Dissolution Team within the Formulation Development Department. This role offers an opportunity to contribute to scientific capabilities while growing into a leadership position on the team.

The successful candidate will lead dissolution studies, design validation protocols, author regulatory submissions, and drive cross-functional collaboration to support late-stage programs and regulatory filings.