Senior Analytical Scientist, Chromatography Expert

Vertex Pharmaceuticals Inc (US); Boston (MA); On-site; USD 122,400 - 183,600; Full time

Job summary

Vertex Pharmaceuticals Inc. in Boston, MA, is seeking a Senior Research Scientist to join Analytical Development. The role leads chromatographic method development, qualification, and validation across clinical development, focusing on small molecules and peptides.

You will partner with cross-functional teams to design and review analytical methods and reports, while mentoring team members. The position requires a Ph.D.

Qualifications

• Deep experience in analytical method development and validation.
• Strong expertise in chromatography and related analytical techniques.
• Ability to troubleshoot, review, and interpret data.
• Solid understanding of GMP and pharmaceutical regulations.

Responsibilities

• Lead chromatographic method development, qualification, and validation activities.
• Partner with cross-functional project teams to design and review analytical methods and reports.
• Serve as a technical expert in chromatographic instrumentation, including detectors and robustness studies.
• Drive continuous improvement in analytical development and validation practices.
• Ensure compliant method development across the organization.
• Mentor staff and contribute to project strategy and scientific progress.

Skills

Analytical method development

Chromatography expertise

LC/GC/LC-MS techniques

Data review & interpretation

Regulatory GMP knowledge

Cross-functional collaboration

Mentorship & training

Education

Ph.D. with 2+ years or Master’s with 5+ years

B.S. with 8+ years in industry (exceptional)

Tools

GC

LC

GC-MS

LC-MS

Karl Fischer

Spectroscopy

Job description

Vertex Pharmaceuticals Inc. in Boston, MA, is seeking a Senior Research Scientist to join Analytical Development. The role leads chromatographic method development, qualification, and validation across clinical development, focusing on small molecules and peptides.

You will partner with cross-functional teams to design and review analytical methods and reports, while mentoring team members. The position requires a Ph.D.