Lead ADC Process Development Scientist

Pfizer

Bothell (WA)

On-site

USD 94,000 - 156,000

Full time

14 days+
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Job summary

Pfizer is seeking a Senior Scientist to lead antibody-drug conjugate (ADC) process development projects from early-phase to late-stage or commercial products. You will mentor team members and forecast resources while applying cutting-edge design and process development capabilities to accelerate breakthrough therapies.

The role emphasizes Quality and cross-functional collaboration. The position is on premise with a base salary range and bonus eligibility, reflecting location-based compensation.

Qualifications

  • Must Have Bachelor's Degree with 9 to11 years of experience, Master's Degree with 7 to 8 years of experience, or PhD and 0-3 years of experience
  • Direct experience with antibodies, proteins, and/or bioconjugation
  • Good understanding of analytical protein characterization (HPLC, IEF, CE-SDS)
  • Willingness to work with highly potent cytotoxic molecules
  • Ability to perform complex data analysis
  • Excellent oral and written communication skills
  • Foundational understanding of organic chemistry, reaction mechanisms, and process development

Responsibilities

  • Independently design, execute, and interpret studies intended to answer a defined question within the defined timeframe.
  • Design subsequent experiments upon interpretation of data.
  • Monitor results, identify problems, and develop solutions.
  • Facilitate technology/assay transfers internally/externally.
  • Regularly contribute at department and project team level and represent the group on multidisciplinary teams.
  • May present at national/international forums.
  • Author and review technical reports, manufacturing documents, regulatory submissions and publications.
  • Identify areas for process improvement and technology development and propose solutions.

Skills

Antibody conjugation
Protein analytics
Data analysis
Oral and written communication

Education

Bachelor's degree in chemistry/biochemistry/chemical engineering
Master's degree
PhD (optional)

Tools

JMP
GMP manufacturing
Tangential flow filtration

Job description

Pfizer is seeking a Senior Scientist to lead antibody-drug conjugate (ADC) process development projects from early-phase to late-stage or commercial products. You will mentor team members and forecast resources while applying cutting-edge design and process development capabilities to accelerate breakthrough therapies.

The role emphasizes Quality and cross-functional collaboration. The position is on premise with a base salary range and bonus eligibility, reflecting location-based compensation.

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