Kidney Genomics Research Specialist: iPSC Organoids CRISPR

University of California, San Francisco; San Francisco (CA); On-site; USD 63,500 - 194,800; Full time

Job summary

The Kidney Genetics, Genomics, and Advanced Models Laboratory at UCSF’s Mission Bay campus is seeking a research specialist with expertise in human stem cell culture and organoid development to advance iPSC‑based kidney disease models.

The role involves engineering iPSCs, performing CRISPR screens, and collaborating across disciplines. Strong emphasis on independent work and career development in a multidisciplinary team is expected.

Qualifications

• Must possess significant experience with iPSC culture, generation of iPSC‑derived cell types or organoids, and immunofluorescence.
• Experience with genome engineering of in‑vitro cell types, scRNA‑sequencing, and CRISPR screens is preferred.
• Assistant rank requires a master’s degree (or equivalent) related to the focus area or a bachelor’s with 3+ years of relevant experience.
• Associate rank requires a master’s degree or 5–10 years of experience with scholarly record.

Responsibilities

• iPSC‑derived Kidney Organoid Research: conduct kidney disease research using iPSC‑derived organoids and enhance ability to run genetic/small molecule screens with organoids.
• Genetically engineer iPSCs to enable screens in organoids.
• CRISPR screens: perform CRISPR screens in kidney organoids.

Skills

iPSC culture

organoid models

immunofluorescence

genome engineering

scRNA-seq

CRISPR screens

collaboration

communication

Education

Master’s degree or equivalent

Bachelor’s degree with 3+ years relevant experience

Master’s degree with 5+ years experience

Job description

The Kidney Genetics, Genomics, and Advanced Models Laboratory at UCSF’s Mission Bay campus is seeking a research specialist with expertise in human stem cell culture and organoid development to advance iPSC‑based kidney disease models.

The role involves engineering iPSCs, performing CRISPR screens, and collaborating across disciplines. Strong emphasis on independent work and career development in a multidisciplinary team is expected.