In Vivo Pharmacology Scientist

System One; Boston (MA); On-site; USD 72,000 - 79,000; Full time

Job summary

System One, Inc. is seeking an In Vivo Pharmacology Scientist for a 12-month onsite contract in Boston, MA. The role focuses on executing in vivo studies to support gene therapy candidates, involving rodent models and cross-functional collaboration.

The candidate will design experiments, analyze data, and document findings in line with quality standards, with a flexible schedule including occasional night/weekend hours as needed.

Qualifications

• Hands-on rodent handling, dosing and blood collection in mice and rats (SC/IV/IP injections).
• Experience with gross necropsies, tissue dissection, and processing.

Responsibilities

• Design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance in rodent models.
• Develop and characterize in vivo models.
• Collaborate with Preclinical, toxicology, and PK/PD teams to translate discovery to development.
• Provide written and verbal results in reports and meetings.
• Maintain accurate electronic notebooks per company procedures and GxP standards.
• Ensure compliance with health and safety regulations.

Skills

Rodent handling

In vivo pharmacology

Data analysis

Team collaboration

Education

B.S./M.S. in life sciences

Job description

Job Title: In Vivo Pharmacology Scientist

Location: Boston, MA

Work Model: Onsite

Hours: Monday-Friday 8am to 5pm

Compensation: $52.00 - $57.25/hr

Type: 12-month contract, Potential for extension or conversion to permanent

Overview

The In Vivo Pharmacology Scientist will participate in the Gene Therapy in vivo pharmacology lab to execute experiments in support of the discovery and optimization of novel therapeutic candidates for genetic medicines.

Responsibilities

• Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including mice, rats, and immuno-compromised animals.
• Assist in the development and characterization of novel in vivo models.
• Collaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure the translation from discovery to development.
• Provide written and verbal communication of work in study reports and team meetings.
• Keep and maintain accurate and timely documentation of all practical work: completion of electronic notebook in alignment with company procedure quality standards and Good Documentation Practices.
• Ensure compliance with all health and safety regulations.

Requirements

• B.S/MS in life sciences (e.g., biology, neuroscience, or related field) or 3-5 years experience working in pharmaceutical industry or contract research organization.

• Additional Skills/Preferences:
• Hands on experience of rodent handling, dosing, and blood collection of mice and rats including but not limited to: subcutaneous (SC), intravenous (IV), & intraperitoneal (IP) injections, and submandibular, venipuncture, & cardiac puncture bleeds.
• Experience with gross necropsies, tissue dissection, and trimming and processing.
• Ability to adapt and exercise flexibility for changing platform needs, workflows, and projects including the availability to provide the occasional night, weekend, or holiday hours.
• Ability to craft, complete and interpret experiments independently, and to advance scientific understanding.
• Excellent communication skills and effective in collaborating across functional boundaries and in team environment.
• Strong organization skills, attention to detail, critical thinking, multitasking, desire to learn new techniques and contribute to innovative projects in a fast-paced working environment.
• Experience in processing, organizing, analyzing and visualizing data and information from disparate sources and ability to extract insight from data.

System One, and its subsidiaries including Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality.

System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

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Ref: #558-Scientific