Biologist – In Vivo Pharmacology

Binding Minds Inc. (Certified Disability Owned Business Enterprise); Boston (MA); On-site; USD 55,000 - 75,000; Full time

Job summary

Binding Minds Inc. is seeking a Biologist to join an in vivo pharmacology lab to execute experiments supporting discovery and optimization of genetic medicines. The role involves rodent studies (mice, rats) and collaboration across Preclinical and PK/PD teams.

Candidates should have a B.S./M.S. in life sciences or 3–5 years of pharma/CRO experience, hands-on rodent handling, injections, necropsies, and strong data analysis and documentation skills, with excellent communication and teamwork.

Qualifications

• B.S./M.S. in life sciences or 3–5 years’ experience in the pharmaceutical industry or a contract research organization.
• Hands-on rodent handling, dosing and blood collection in mice and rats including SC, IV, IP injections.
• Experience with gross necropsies, tissue dissection and processing.
• Ability to adapt to changing platform needs and workflows, including potential night, weekend or holiday hours.
• Strong communication and collaboration across functional boundaries and in a team.
• Experience extracting insights from data from disparate sources.

Responsibilities

• Design and execute in vivo pharmacology experiments to characterize activity, distribution and clearance of genetic medicines in rodent models.
• Assist in development and characterization of novel in vivo models.
• Collaborate with Preclinical, toxicology and PK/PD teams to translate discovery to development.
• Provide written and verbal communication in study reports and team meetings.
• Maintain accurate documentation and electronic notebooks in line with quality standards.
• Ensure compliance with health and safety regulations.

Skills

Rodent handling

Data analysis

Communication

Documentation

Education

B.S./M.S. in life sciences

Job description

Job Type: 12 Months Contract (Possible Extension)

We are looking for a Biologist to participate in an in vivo pharmacology lab and execute experiments in support of the discovery and optimization of novel therapeutic candidates for genetic medicines.

Key Responsibilities

• Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including mice, rats, and immuno-compromised animals.
• Assist in the development and characterization of novel in vivo models.
• Collaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure the translation from discovery to development.
• Provide written and verbal communication of work in study reports and team meetings.
• Keep and maintain accurate and timely documentation of all practical work, including completion of electronic notebooks in alignment with quality standards and Good Documentation Practices.
• Ensure compliance with all health and safety regulations.

Qualifications

• B.S./M.S. in life sciences (e.g., biology, neuroscience, or related field) or 3-5 years of experience working in the pharmaceutical industry or a contract research organization.
• Hands-on experience with rodent handling, dosing, and blood collection of mice and rats, including but not limited to:
• Subcutaneous (SC), intravenous (IV), and intraperitoneal (IP) injections.
• Submandibular, venipuncture, and cardiac puncture bleeds.
• Experience with gross necropsies, tissue dissection, trimming, and processing.
• Ability to adapt and exercise flexibility for changing platform needs, workflows, and projects, including occasional night, weekend, or holiday hours.
• Ability to craft, complete, and interpret experiments independently and advance scientific understanding.
• Excellent communication skills and ability to collaborate across functional boundaries and in a team environment.
• Strong organizational skills, attention to detail, critical thinking, and multitasking abilities.
• Desire to learn new techniques and contribute to innovative projects in a fast-paced working environment.
• Experience in processing, organizing, analyzing, and visualizing data and information from disparate sources and ability to extract insights from data.