In Vivo Oncology Scientist — Immuno-Oncology & Mouse Models

Pattern Biosciences

South San Francisco (CA)

On-site

USD 170,000 - 210,000

Full time

3 days ago

Be an early applicant

A complete application in a minute

Tailored resume and cover letter, ready to send.

Get past ATS filters

Job summary

Pattern Biosciences seeks a highly skilled scientist to design and execute in vivo mouse studies of AAV-based cancer therapeutic candidates, advancing our oncology pipeline and platform. You will contribute to preclinical study design and lead execution with strong scientific rigor.

The role requires expertise in immuno-oncology, in vivo pharmacology, and cross-disciplinary collaboration within a team environment. Experience with rodent surgery, tissue handling, and immune profiling is essential.

Qualifications

PhD in Life Sciences with specialization in oncology or immunology.
At least 3 years of hands-on experience with murine tumor models in industry or academia.
Proven ability to design, execute and interpret in vivo experiments.
Experience with rodent surgery and IV dosing.
Experience with tissue handling, cell sorting, multicolor flow cytometry, cytokine profiling; IHC/ISH is a plus.

Responsibilities

Design and execute in vivo studies in preclinical tumor models to evaluate mechanism of action, efficacy and safety of therapeutic candidates.
Perform in vivo procedures including orthotopic tumor implantation, IV and IP injections, blood sampling, in vivo imaging, and welfare monitoring.
Perform necropsy, tissue collection and processing for IHC or histopathology, tissue dissociation and cell sorting for downstream assays.
Conduct immune cell profiling using multicolor flow cytometry, and cytokine/chemokine analysis using ELISA and Luminex.
Generate, document, analyze and interpret experimental data to support critical decisions on lead candidates.
Manage external laboratories and partners.