Immunotherapy Scientist II – CAR/TCR Discovery

Dana-Farber Cancer Institute (DFCI); Boston (MA); On-site; USD 85,000 - 105,000; Full time

Job summary

Dana-Farber Cancer Institute in Boston, MA is seeking a Scientist II in the Freed-Pastor Laboratory to join the Cancer Grand Challenges—Team ILLUMINE, focusing on exploring the Cancer Dark Proteome and advancing innovative cellular therapies for pancreatic cancer.

This hands-on bench role emphasizes rigorous data generation, experimental execution, and collaboration across a multi-institutional team, with ownership of essential laboratory operations and contribution toward clinical trial

Qualifications

• Advanced degree preferred.
• Six to nine years experience post undergraduate degree.
• One to two year work experience post education.

Responsibilities

• Independently design, execute, and analyze experiments focusing on discovery and characterization of T-cell receptors (TCRs) and chimeric antigen receptors (CARs).
• Conduct rigorous ex vivo and in vivo preclinical studies of lead cellular therapy candidates with meticulous data collection and analysis.
• Establish and utilize patient-derived organoids and patient-derived xenografts for antigen discovery and preclinical testing.
• Perform rigorous data analysis, interpretation, and presentation of results at lab meetings; contribute to manuscripts and conference presentations.
• Demonstrate technical proficiency, creativity, collaboration, and independent thought on problems of moderate to large scope.
• Work with minimal supervision and maintain wide latitude for independent judgment.

Education

Advanced degree (preferred)

Six to nine years experience post undergraduate

One to two year work experience post education

Job description

Dana-Farber Cancer Institute in Boston, MA is seeking a Scientist II in the Freed-Pastor Laboratory to join the Cancer Grand Challenges—Team ILLUMINE, focusing on exploring the Cancer Dark Proteome and advancing innovative cellular therapies for pancreatic cancer.

This hands-on bench role emphasizes rigorous data generation, experimental execution, and collaboration across a multi-institutional team, with ownership of essential laboratory operations and contribution toward clinical trial