Immunogenomics Scientist: Target Discovery & Molecular Engineering

Genentech; South San Francisco (CA); On-site; USD 103,000 - 192,000; Full time

Benefits offered by this job

Relocation benefits

Job summary

Genentech is seeking a Scientist 3 within the CTG to advance target discovery through state-of-the-art genomics, functional readouts, and molecular engineering in immune-mediated diseases.

The role combines technology development with disease biology, requiring collaboration across immunology, genomics, and computational biology. A strong publication and/or patent record is valued, and relocation benefits are available.

Qualifications

• PhD in molecular biology, genetics, immunology, or related field.
• Experience with immunology and primary immune cell culture; in vivo experience is a plus.
• Experience deploying molecular engineering tools at scale in primary immune cells or iPSCs.

Responsibilities

• Develop and deploy molecular engineering technologies and read-outs.
• Interrogate immunological disease mechanisms at scale to identify targets and cell therapy strategies.
• Collaborate with multidisciplinary teams across immunology, genomics, computational biology, and AI/ML.

Skills

Immunology expertise

Molecular engineering

Leadership

Scientific productivity

Problem solving

Communication skills

Computational analyses

Single-cell genomics

Education

PhD in a relevant field

Tools

CRISPR (CRISPRko, CRISPRi/a)

Deep mutational scanning

Lineage tracing

Molecular recorders

NGS / genomics tools

Job description

Genentech is seeking a Scientist 3 within the CTG to advance target discovery through state-of-the-art genomics, functional readouts, and molecular engineering in immune-mediated diseases.

The role combines technology development with disease biology, requiring collaboration across immunology, genomics, and computational biology. A strong publication and/or patent record is valued, and relocation benefits are available.