Histology Scientist - IHC & In Situ (Boston)

WorkLLama; Boston (MA); On-site; USD 85,000 - 110,000; Full time

Job summary

WorkLLama in Boston seeks a hands-on scientist with immunohistochemistry expertise to join our Exploratory Discovery team. You will contribute to supporting preclinical and clinical development of oncology targets and drugs, driving method development and actively shaping scientific discussions.

Responsibilities include optimizing IHC, IF, and RNAscope assays on FFPE and frozen tissue, tissue processing and sectioning, building archival FFPE libraries, image acquisition, and data analysis with

Qualifications

• Requires hands-on experience in immunohistochemistry and in situ hybridization.
• Experience with FFPE and frozen tissue processing and sectioning.
• Familiarity with automated stainers and image analysis platforms is a plus.

Responsibilities

• Optimize, validate, and execute IHC, IF, and RNAscope assays with appropriate controls.
• Perform tissue processing and sectioning of FFPE and frozen blocks.
• Build and manage archival FFPE specimen libraries.
• Characterize compound/antibody activity using biomarker histology.
• Perform image acquisition and basic microscopy, with open-source or commercial analysis tools.
• Analyze complex datasets and communicate findings to teams.
• Troubleshoot technical hurdles and contribute to method development.
• Maintain sample tracking and data workflows (LIMS).

Skills

Immunohistochemistry

Immunofluorescence

In situ hybridization

Tissue processing

Data analysis

Statistics

Troubleshooting

Method development

Education

Associate degree / BS / MS in a relevant scientific discipline

Tools

Leica Bond

Phenocycler

COMET

LIMS

Whole slide imaging

Job description

WorkLLama in Boston seeks a hands-on scientist with immunohistochemistry expertise to join our Exploratory Discovery team. You will contribute to supporting preclinical and clinical development of oncology targets and drugs, driving method development and actively shaping scientific discussions.

Responsibilities include optimizing IHC, IF, and RNAscope assays on FFPE and frozen tissue, tissue processing and sectioning, building archival FFPE libraries, image acquisition, and data analysis with